Evidence map›Paper›PMID 38076033›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2023

Samira Saeirad, Mark S LeDoux

Open access · goldAbstract read
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Clinical implications of genetic polymorphisms in blepharospasm.Experimental and therapeutic medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Samira SaeiradUniversity of Memphis, Memphis, Tennessee, USA.ORCID 0000-0001-8979-0085
Mark S LeDouxUniversity of Memphis, Memphis, Tennessee, USA.ORCID 0000-0002-1748-3390
Texas Neurology · US

Funding

Pathobiology and Treatment of the UBTF E210K Neuroregression SyndromeR56NS123059 · NINDS · UNIVERSITY OF MEMPHIS · PI LEDOUX, MARK S · 2021 to 2021
$415k
Pathobiology of GNAL-Associated DystoniaR21NS123827 · NINDS · UNIVERSITY OF MEMPHIS · PI LEDOUX, MARK S · 2022 to 2023
$395k
NINDS NIH HHS R21 NS123827NINDS NIH HHS R56 NS123059
6 · The paper itself

Abstract

Background: Genetic factors have been implicated in the pathogenesis of blepharospasm (BSP), a dystonia characterized by excessive blinking and involuntary eyelid closure. Previous research identified a co-segregating deleterious Methods: Sanger sequencing was used to screen a cohort of 307 subjects with isolated BSP or BSP-plus dystonia affecting additional anatomical segments (BSP+). We also utilized computational tools to uniformly assess the deleteriousness and potential pathogenicity of previously reported Results: There were no highly deleterious Discussion: Highly deleterious variants in Highlights: Over 300 patients with BSP were screened for variants in

Indexed as

BlepharospasmDystoniaDystonic DisordersHumansIntercellular Signaling Peptides and ProteinsMolecular ChaperonesPedigreeIntercellular Signaling Peptides and ProteinsMolecular ChaperonesTOR1A protein, humanTOR2A protein, humanblepharospasmdystoniaSanger sequencingTOR2Avariant analysis

Identifiers

PMID38076033
PMCPMC10705022
OpenAlexW4389494290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.