Evidence map›Paper›PMID 38075970›Full record

ArticleFrontiers in cardiovascular medicine2023

Echocardiographic functional determinants of survival in heart failure with abnormal ejection fraction.

Quirino Ciampi, Lauro Cortigiani, Nicola Gaibazzi, Fausto Rigo, Angela Zagatina, Karina Wierzbowska-Drabik, Jaroslaw D Kasprzak, Ana Djordjevic-Dikic, Maciej Haberka, Andrea Barbieri and 6 more

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Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Quirino CiampiCardiology Department, Fatebenefratelli Hospital of Benevento, Benevento, Italy.
Lauro CortigianiCardiology Department, San Luca Hospital, Lucca, Italy.
Nicola GaibazziCardiology Department, Villa Salus Foundation/IRCCS San Camillo Hospital, Venice, Italy.
Fausto RigoCardiology Department, University of Parma, Parma, Italy.
Angela ZagatinaCardiology Department, Research Cardiology Center "Medika", Saint Petersburg, Russian Federation.
Karina Wierzbowska-DrabikDepartment of Internal Disease and Clinical Pharmacology, Medical University, Lodz, Poland.
Jaroslaw D KasprzakDepartment of Cardiology, Medical University of Lodz, BieganskiSpecialty Hospital, Lodz, Poland.
Ana Djordjevic-DikicClinical Center of Serbia and School of Medicine, University of Belgrade, Cardiology Clinic, Belgrade, Serbia.
Maciej HaberkaCardiology Department, University of Silesia, Katowice, Poland.
Andrea BarbieriCardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy.
Ylenia BartolacelliPaediatric Cardiology and Adult Congenital Heart Disease Unit, S. Orsola-Malpighi Hospital, Bologna, Italy.
Mauro PepiCardiology Division, Centro Cardiologico Monzino, IRCCS, Milano, Italy.
Scipione CarerjCardiology Division, University Hospital Polyclinic G.Martino, University of Messina, Messina, Italy.
Bruno VillariCardiology Department, Fatebenefratelli Hospital of Benevento, Benevento, Italy.
Patricia A PellikkaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.
Eugenio PicanoBiomedicine Department, CNR, Institute of Clinical Physiology, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Patients with heart failure (HF) with reduced left ventricular (LV) ejection fraction (EF) have a heterogeneous prognosis, and assessment of coronary physiology with coronary flow velocity (CFV) and coronary flow velocity reserve (CFVR) may complement established predictors based on wall motion and EF. Methods and results: In a prospective multicenter study design, we enrolled 1,408 HF patients (age 66 ± 12 years, 1,035 men), with EF <50%, 743 (53%) with coronary artery disease, and 665 (47%) with normal coronary arteries. Recruitment (years 2004-2022) involved 8 accredited laboratories, with inter-observer variability <10% for CFV measurement. Baseline CFV (abnormal value >31 cm/s) was obtained by pulsed-wave Doppler in mid-distal LAD. CFVR (abnormal value ≤2.0) was assessed with exercise ( Conclusion: High resting CFV is associated with worse survival in ischemic and nonischemic HF with reduced EF. The value is independent and additive to resting EF, CFVR, LVCR, and inducible ischemia.

Indexed as

contractile reservecoronary flow reservedilated cardiaomypothyheart failiureinfrastructural funding from società italiana di ecocardiografia e cardiovascular imaging (SIECVI)publicationstress echotravel

Identifiers

PMID38075970
PMCPMC10699198

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