Evidence map›Paper›PMID 38075920›Full record

ArticleFrontiers in microbiology2023

Superior efficacy of combination antibiotic therapy versus monotherapy in a mouse model of Lyme disease.

Yasir Alruwaili, Mary B Jacobs, Nicole R Hasenkampf, Amanda C Tardo, Celine E McDaniel, Monica E Embers

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Chronic meningitis: diagnostic and therapeutic challenges.Current opinion in infectious diseases · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Yasir AlruwailiDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia.
Mary B JacobsDivision of Immunology, Tulane National Primate Research Center, Tulane University, Covington, LA, United States.
Nicole R HasenkampfDivision of Immunology, Tulane National Primate Research Center, Tulane University, Covington, LA, United States.
Amanda C TardoDivision of Immunology, Tulane National Primate Research Center, Tulane University, Covington, LA, United States.
Celine E McDanielDivision of Immunology, Tulane National Primate Research Center, Tulane University, Covington, LA, United States.
Monica E EmbersDivision of Immunology, Tulane National Primate Research Center, Tulane University, Covington, LA, United States.
Tulane University · US

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
NIH HHS P51 OD011104
6 · The paper itself

Abstract

Lyme disease (LD) results from the most prevalent tick-borne infection in North America, with over 476,000 estimated cases annually. The disease is caused by

Indexed as

antibioticBorrelia burgdorfericombinationefficacyLyme diseasemouse

Identifiers

PMID38075920
PMCPMC10703379
OpenAlexW4388940464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.