Evidence map›Paper›PMID 38075878›Full record

ArticleFrontiers in microbiology2023

Lactic acid bacterial surface display of scytovirin inhibitors for anti-ebolavirus infection.

Joshua Wiggins, Ngan Nguyen, Wenzhong Wei, Leah Liu Wang, Haley Hollingsead Olson, Shi-Hua Xiang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Algal Lectin Griffithsin Inhibits Ebola Virus Infection.Molecules (Basel, Switzerland) · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joshua Wiggins *Nebraska Center for Virology, Lincoln, NE, United States.
Ngan Nguyen *Nebraska Center for Virology, Lincoln, NE, United States.
Wenzhong WeiNebraska Center for Virology, Lincoln, NE, United States.
Leah Liu WangNebraska Center for Virology, Lincoln, NE, United States.
Haley Hollingsead OlsonNebraska Center for Virology, Lincoln, NE, United States.
Shi-Hua XiangNebraska Center for Virology, Lincoln, NE, United States.
University of Nebraska–Lincoln · USTexas College · US

Funding

Neuroimmunology of Disease Training ProgramT32NS105594 · NINDS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Aditya N Bade, Howard E Gendelman · 2018 to 2026
$1.4M
Mucosal Delivery and Retention of Ebola Inhibitor Scytovirin Using LactobacillusR21AI126299 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI XIANG, SHI-HUA · 2017 to 2018
$453k
NIAID NIH HHS R21 AI126299NINDS NIH HHS T32 NS105594
6 · The paper itself

Abstract

Scytovirin (SVN) is a lectin from cyanobacteria which has a strong inhibitory activity against Ebola virus infection. We engineered scytovirin as the inhibitor for surface display of lactic acid bacteria to block Ebola virus infection. Two different bacterial strains (

Indexed as

bacterial engineeringEbola viruslactic acid bacterialectinsscytovirinsurface display

Identifiers

PMID38075878
PMCPMC10704896
OpenAlexW4388939502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.