Evidence map›Paper›PMID 38075847›Full record

ReviewWorld journal of gastroenterology2023

Role of exosomes in metastasis and therapeutic resistance in esophageal cancer.

Xing-Yu Ning, Jin-Hu Ma, Wei He, Jun-Ting Ma

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xing-Yu NingThe Second School of Clinical Medicine, Anhui Medical University, Hefei 230032, Anhui Province, China.
Jin-Hu MaThe Second School of Clinical Medicine, Anhui Medical University, Hefei 230032, Anhui Province, China.
Wei HeSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, Anhui Province, China.
Jun-Ting MaSchool of Basic Medical Sciences, Anhui Medical University, Hefei 230032, Anhui Province, China. 1064363840@qq.com.
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal cancer (EC) has a high incidence and mortality rate and is emerging as one of the most common health problems globally. Owing to the lack of sensitive detection methods, uncontrollable rapid metastasis, and pervasive treatment resistance, EC is often diagnosed in advanced stages and is susceptible to local recurrence. Exosomes are important components of intercellular communication and the exosome-mediated crosstalk between the cancer and surrounding cells within the tumor microenvironment plays a crucial role in the metastasis, progression, and therapeutic resistance of EC. Considering the critical role of exosomes in tumor pathogenesis, this review focused on elucidating the impact of exosomes on EC metastasis and therapeutic resistance. Here, we summarized the relevant signaling pathways involved in these processes. In addition, we discussed the potential clinical applications of exosomes for the early diagnosis, prognosis, and treatment of EC.

Indexed as

Esophageal NeoplasmsExosomesCell CommunicationDrug Resistance, NeoplasmHumansSignal TransductionTumor MicroenvironmentEsophageal cancerExosomesMetastasisSignaling pathwayTherapeutic resistanceTumor microenvironment

Identifiers

PMID38075847
PMCPMC10701334
OpenAlexW4388580744

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.