Evidence map›Paper›PMID 38075798›Full record

ArticleACS omega2023

Gelatin-Based Hydrogel for Three-Dimensional Neuron Culture Application.

Yu-Yun Gao, You-Ren Ji, Yi-Hua Hsu, Fang-Chun Liao, Nien-Tzu Kao, Abel Po-Hao Huang, Tai-Horng Young

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Peripheral nerve repair: innovations and future directions.Journal of translational medicine · 2026
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yu-Yun GaoDepartment of Biomedical Engineering, National Taiwan University, Taipei 100, Taiwan.
You-Ren JiDepartment of Biomedical Engineering, National Taiwan University, Taipei 100, Taiwan.
Yi-Hua HsuDepartment of Surgery, National Taiwan University Hospital and College of Medicine, Taipei 100, Taiwan.
Fang-Chun LiaoDepartment of Biomedical Engineering, National Taiwan University, Taipei 100, Taiwan.
Nien-Tzu KaoDepartment of Biomedical Engineering, National Taiwan University, Taipei 100, Taiwan.
Abel Po-Hao HuangDepartment of Surgery, National Taiwan University Hospital and College of Medicine, Taipei 100, Taiwan.
Tai-Horng YoungDepartment of Biomedical Engineering, National Taiwan University, Taipei 100, Taiwan.ORCID https://orcid.org/0000-0001-5338-4747
National Taiwan University · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gelatin is a biocompatible biomaterial composed of a variety of amino acids that provides a possibility to regulate the interaction between cationic amino acids and neural cells. Based on our first finding that the neuron viability was improved as the lysine on the gelatin was converted into a guanidine structure, a three-dimensional (3D) gelatin hydrogel composed of gelatin and poly(allylguanidine) (PAG) was prepared to investigate neural cell behaviors. As expected, improved neuron viability, neurite outgrowth, synaptogenesis, and inhibited glial cell growth were simultaneously observed in the gelatin cross-linked with the PAG hydrogel (G-PAG) but not in the gelatin hydrogel cross-linked with poly-d-lysine (PDL) or polyethylenimine (PEI). In addition,

Identifiers

PMID38075798
PMCPMC10702320
OpenAlexW4388760412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.