Evidence map›Paper›PMID 38075542›Full record

ArticleContemporary clinical dentistry

Clinical, Histological, and Molecular Perspective on Regenerating Nonvital Immature Teeth.

García-Guerrero Claudia, Mora-Pinza Tania, Quijano-Guauque Sara, Leal-Fernández Carolina, Baldión-Elorza Paula

Open access · goldAbstract read
In one paragraph

Article in Contemporary clinical dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

García-Guerrero ClaudiaDepartamento de Ciencias Básicas y Medicina Oral, Facultad de Odontología, Universidad Nacional de Colombia, Grupo de Investigación INVENDO, Bogotá, Colombia.
Mora-Pinza TaniaDepartamento de Ciencias Básicas y Medicina Oral, Facultad de Odontología, Universidad Nacional de Colombia, Grupo de Investigación INVENDO, Bogotá, Colombia.
Quijano-Guauque SaraDepartamento de Ciencias Básicas y Medicina Oral, Facultad de Odontología, Universidad Nacional de Colombia, Grupo de Investigación INVENDO, Bogotá, Colombia.
Leal-Fernández CarolinaDepartamento de Dentario, Facultad de Odontología, Pontificia Universidad Javeriana, Bogotá, Colombia.
Baldión-Elorza PaulaDepartamento de Salud Oral, Facultad de Odontología, Universidad Nacional de Colombia, Grupo de Investigación INVENDO, Bogotá, Colombia.
Universidad Nacional de Colombia · COPontificia Universidad Javeriana · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Disinfection and dentin conditioning promote a favorable scenario for regenerative endodontic treatment. Clinical reports have confirmed periapical normality with high variability in disinfection protocols; nevertheless, the nature of neoformed tissue varied between them. Thus, this study aimed to present the impact of disinfection protocols on the clinical, histological, and molecular outcomes of regenerative endodontics procedures in permanent teeth with incomplete root formation. Materials and Methods: Eighteen teeth with incomplete root formation which required endodontic regenerative treatment were treated with different disinfection and conditioning agents and followed under clinical control. One case was evaluated under histological and immunohistochemical analyses. Results: Clinical outcomes revealed periapical repair in 17/18 cases. Histological and immunohistochemical analyses confirmed the neoformation of the dentinal matrix and its mineralization. Conclusions: Chemical conditioning could impact the outcome of regenerative endodontic procedures. The histological and immunohistochemical analysis showed the nature of the newly formed tissue that correlates with the clinical outcome.

Indexed as

Dentin matrix protein-1dentin sialoproteinhumannonvitalregenerative endodonticsroot canal irrigantstooth

Identifiers

PMID38075542
PMCPMC10699185
OpenAlexW4388265291

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.