ArticleContemporary clinical dentistry
Article in Contemporary clinical dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Anti-cancer effects of plant extracts in head and neck squamous cell carcinoma.Frontiers in pharmacology · 2026Review
- Cytotoxic and apoptotic effects of novel phytochemical extracts on oral squamous cell carcinoma cells.Bioinformation · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Due to their wide spectrum of phytochemical components and lack of side effects, the use of plants for the prevention and treatment of cancer has recently attracted increased attention. One among them is Aim: In the present study, we aimed to investigate the cytotoxic potential of leaf extract of Materials and Methods: 3-(4,5-dimethylthiazol-2-yl)-2,5-dipenyltetrazolium bromide assay was performed to assess cytotoxic activity, and the apoptotic effect was determined using gene expression analyses of Bcl 2-associated X protein (Bax), B-cell C/lymphoma 2 (Bcl-2), and tumor-suppressor phosphoprotein (p53). Results: Significant cytotoxicity ( Conclusion: These results show that LEAM has the potential for development as a therapeutic agent for cytotoxicity, particularly on oral SCC cells, following further investigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.