Evidence map›Paper›PMID 38075457›Full record

ArticleJournal of orthopaedics2024

Interobserver variability in the determination of bone mineral density in Hounsfield units from differently configured fields of measurement in the cancellous bone of vertebral bodies from elderly body donors.

Guido Schröder, Julian Ramin Andresen, Laura Hiepe, Marko Schulze, Claus Maximilian Kullen, Christoph Kopetsch, Jens Burmeister, Hans-Christof Schober, Reimer Andresen

Open access · greenAbstract read
In one paragraph

Article in Journal of orthopaedics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 11 citations in OpenAlex.

  1. Multi-center validation of automated CT-based L1 vertebral Hounsfield unit.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Guido SchröderCenter for Orthopaedics, Trauma Surgery and Rehabilitation Medicine, Greifswald University Medical Center, Germany.
Julian Ramin AndresenDepartment of Orthopedics and Trauma Surgery, Medical University of Vienna, Vienna, Austria.
Laura HiepeInstitute of Anatomy, Rostock University Medical Center, Rostock, Germany.
Marko SchulzeInstitute of Anatomy and Cell Biology, University of Bielefeld, Bielefeld, Germany.
Claus Maximilian KullenInstitute of Diagnostic and Interventional Radiology / Neuroradiology, Westkuestenklinikum Heide, Academic Teaching Hospital of the Universities of Kiel, Luebeck and Hamburg, Heide, Germany.
Christoph KopetschInstitute of Diagnostic and Interventional Radiology / Neuroradiology, Westkuestenklinikum Heide, Academic Teaching Hospital of the Universities of Kiel, Luebeck and Hamburg, Heide, Germany.
Jens BurmeisterClinic of Internal Medicine IV, Klinikum Südstadt Rostock, Academic Teaching Hospital of the University of Rostock, Rostock, Germany.
Hans-Christof SchoberClinic of Internal Medicine IV, Klinikum Südstadt Rostock, Academic Teaching Hospital of the University of Rostock, Rostock, Germany.
Reimer AndresenInstitute of Diagnostic and Interventional Radiology / Neuroradiology, Westkuestenklinikum Heide, Academic Teaching Hospital of the Universities of Kiel, Luebeck and Hamburg, Heide, Germany.
Klinikum Südstadt Rostock · DEBielefeld University · DEMedical University of Vienna · ATUniversitätsmedizin Greifswald · DEUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Due to the absence of suitable diagnostic procedures, osteoporosis (OP) is frequently detected late or not at all. Many elderly persons undergo computed tomographies (CT). The routine determination of Hounsfield units (HU) in bone as a part of these examinations could close a gap here. Methods: Spines were extracted from 22 body donors, fixed in a PVC water phantom, and subjected to a high-resolution CT investigation. Cancellous bone was examined and its bone mineral density measured in HU from cervical vertebra 3 to lumbar vertebra 5 (484 vertebral bodies). On sagittal sections, a circular and a rectangular region of interest (ROI) were defined in mid-vertebral cancellous bone, positioned manually, and the measurements were performed by three experienced radiologists. Bone mineral density (BMD), measured in mg/cm Results: All of the spines were osteoporotic. In the presence of a BMD below 60 mg/cm Conclusions: Measurement of the density of cancellous bone in HU can be used to determine BMD for estimating demineralization. Quantitative BMD values in mg/cm

Indexed as

Bone density measurementBone mineral content measurementHounsfield unitsInterobserver variabilityOsteoporosis

Identifiers

PMID38075457
PMCPMC10698493
OpenAlexW4388997039

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.