Evidence map›Paper›PMID 38075432›Full record

ArticleVaccine: X2023

Long-term immunity induced by SPBN GASGAS in orally vaccinated dogs is non-inferior to inactivated rabies vaccines.

Ad Vos, Suwicha Kasemsuwan, Kansuda Leelahapongsathon, Katharina Bobe, David Perez-Bravo, Jeannette Kliemt, Parinya Phawaphutayanchi, Nirut Aiyara, Conrad M Freuling, Thomas Müller

Open access · goldAbstract read
In one paragraph

Article in Vaccine: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Feasibility of Oral Rabies Vaccination of Dogs in Mexico.Tropical medicine and infectious disease · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ad VosCeva Innovation Center, 06861 Dessau-Rosslau, Germany.
Suwicha KasemsuwanFaculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.
Kansuda LeelahapongsathonFaculty of Veterinary Medicine, Kasetsart University, Bangkok 10900, Thailand.
Katharina BobeCeva Innovation Center, 06861 Dessau-Rosslau, Germany.
David Perez-BravoCeva Innovation Center, 06861 Dessau-Rosslau, Germany.
Jeannette KliemtInstitute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut (FLI), WHO Collaborating Centre for Rabies Surveillance and Research, 17493 Greifswald-Insel Riems, Germany.
Parinya PhawaphutayanchiDepartment of Health, Bangkok Metropolitan, Thapthan 61120, Thailand.
Nirut AiyaraDepartment of Health, Bangkok Metropolitan, Thapthan 61120, Thailand.
Conrad M FreulingInstitute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut (FLI), WHO Collaborating Centre for Rabies Surveillance and Research, 17493 Greifswald-Insel Riems, Germany.
Thomas MüllerInstitute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut (FLI), WHO Collaborating Centre for Rabies Surveillance and Research, 17493 Greifswald-Insel Riems, Germany.
Friedrich-Loeffler-Institut · DEGerman Environment Agency · DEBangkok Metropolitan Administration · THKasetsart University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a long-term immunogenicity study (1100 days post vaccination) in local Thai dogs the immune response of the oral rabies vaccine SPBN GASGAS was compared to those elicited by a commercial inactivated vaccine using immunobridging. Based on the detection of rabies virus binding (rVBA) and rabies virus neutralizing antibodies (rVNA) as measured by ELISA and Rapid Fluorescent Focus Inhibition Test (RFFIT) the long-term immune response in dogs vaccinated orally with the SPBNA GASGAS strain of rabies vaccine in a bait was non-inferior to a conventional inactivated rabies vaccine. The outcome of this study supports extending the originally claimed duration of immunity (DOI) of SPBN GASGAS after oral vaccination for dogs from 6 to 30 months.

Indexed as

DogDOIEfficacyImmunobridgingOral vaccinationSPBN GASGAS

Identifiers

PMID38075432
PMCPMC10698526
OpenAlexW4388840354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.