Evidence map›Paper›PMID 38075418›Full record

ArticleLe infezioni in medicina2023

Disinfectant caps

Sara Giordana Rimoldi, Leyla La Cava, Chiara Palladino, Mariagrazia Piacenza, Stefania Vimercati, Pagani Cristina, Federica Salari, Daniele Curreli, Maria Rita Gismondo, Antonella Foschi and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Le infezioni in medicina, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 67% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Sara Giordana RimoldiMicrobiology, Virology and Bioemergency Unit, ASST Fatebenefratelli Sacco, Milan, Italy.
Leyla La CavaDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Luigi Sacco Hospital, Milan, Italy.
Chiara PalladinoPharmacy Unit, ASST Fatebenefratelli-Sacco, Milan, Italy.
Mariagrazia PiacenzaPharmacy Unit, ASST Fatebenefratelli-Sacco, Milan, Italy.
Stefania VimercatiPharmacy Unit, ASST Fatebenefratelli-Sacco, Milan, Italy.
Pagani CristinaMicrobiology, Virology and Bioemergency Unit, ASST Fatebenefratelli Sacco, Milan, Italy.
Federica SalariMicrobiology, Virology and Bioemergency Unit, ASST Fatebenefratelli Sacco, Milan, Italy.
Daniele CurreliMicrobiology, Virology and Bioemergency Unit, ASST Fatebenefratelli Sacco, Milan, Italy.
Maria Rita GismondoMicrobiology, Virology and Bioemergency Unit, ASST Fatebenefratelli Sacco, Milan, Italy.
Antonella FoschiDepartment of Infectious Diseases, Luigi Sacco Hospital, Milan, Italy.
Davide GiustiviVascular Access Team, ASST Lodi, Italy.
Veronica DiottoPediatric Anesthesia and Intensive Care Unit, "Vittore Buzzi" Children Hospital, Milan, Italy.
Emanuele BizziInternal Medicine Department, Fatebenefratelli Hospital, Milan, Italy.
Maria CalloniDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Luigi Sacco Hospital, Milan, Italy.
Francesco CasellaDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Luigi Sacco Hospital, Milan, Italy.
Elena MartiniDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Luigi Sacco Hospital, Milan, Italy.
Mattia DonadoniDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Luigi Sacco Hospital, Milan, Italy.
Chiara CogliatiDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Luigi Sacco Hospital, Milan, Italy.
Antonio GidaroDepartment of Biomedical and Clinical Sciences "Luigi Sacco", University of Milan, Luigi Sacco Hospital, Milan, Italy.
Luigi Sacco Hospital · ITUniversity of Milan · ITAziende Socio Sanitarie Territoriale LodiFatebenefratelli Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Catheter-related bloodstream infections (CRBSIs) are a major cause of morbidity and mortality among hospitalized patients. Different studies suggest that the use of disinfectant caps (DCs) significantly reduces the rate of CRBSIs. The first purpose of this study is to analyze, through an Methods: A know concentration of thirteen different microorganisms was incubated with the sponge drenched in antimicrobial fluid inside DCs and cultured through several assays to investigate the disinfectant effectiveness of some commercially available caps. Disinfectant properties were evaluated under two different conditions: baseline (DCs placed on the needle-free connectors (NFCs) and stress test (DCs directly applied to the catheter hub). Results: Both manufacturers overcame the basal tests (fourteen different assays). Regarding stress tests: the only significant bacterial load was found for Conclusions: Our results confirm what was reported in BD PureHub™ datasheet and add data not previously shown by ICU Medical™. Moreover, no difference was observed between the two manufacturers products: the use of both DCs on NFCs was able to reclaim the catheter lumen. These findings support the routine use of DCs with NFCs, as part of a structured bundle of interventions, to reduce the incidence of CRBSIs.

Indexed as

Catheter-related bloodstream infections (CRBSIs)disinfectant cap (DCs)in vitro modelneedle-free connectors (NFCs)Port Protector

Identifiers

PMID38075418
PMCPMC10705867
OpenAlexW4389365570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.