Evidence map›Paper›PMID 38075250›Full record

ReviewMaterials today. Bio2023

Nanomaterials as therapeutic agents to modulate astrocyte-mediated inflammation in spinal cord injury.

Wenqi Luo, Yueying Li, Chunyu Xiang, Toshimi Aizawa, Renrui Niu, Yiming Wang, Jianhui Zhao, Zeping Liu, Chaoyuan Li, Wanguo Liu and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Materials today. Bio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Wenqi LuoDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, PR China.
Yueying LiDepartment of Hand and Foot Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, PR China.
Chunyu XiangDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, PR China.
Toshimi AizawaDepartment of Orthopedic Surgery, Tohoku University Graduate School of Medicine, Sendai, 980-8574, Japan.
Renrui NiuDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, PR China.
Yiming WangDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, PR China.
Jianhui ZhaoDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, PR China.
Zeping LiuDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, PR China.
Chaoyuan LiDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, PR China.
Wanguo LiuDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, PR China.
Rui GuDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, PR China.
Union Hospital · CNTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Promoting the recovery of neurological function in patients with traumatic spinal cord injury (TSCI) remains challenging. The balance between astrocyte-mediated neurotrophic and pro-inflammatory responses is critical for TSCI repair. Recently, the utilization of nanomaterials has been considerably explored in immunological reconstructive techniques that specifically target astrocyte-mediated inflammation, yielding positive outcomes. In this review, we aim to condense the present knowledge regarding the astrocyte-mediated inflammation following TSCI. We then review the various categories of nanomaterials utilized in the management of astrocyte-mediated inflammation in TSCI and conclude by summarizing their functions and advantages to offer novel insights for the advancement of effective clinical strategies targeting TSCI.

Indexed as

AstrocyteInflammationNanomaterialsSpinal cord injuryTreatment

Identifiers

PMID38075250
PMCPMC10704436
OpenAlexW4389117155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.