Evidence map›Paper›PMID 38075243›Full record

ArticleMolecular therapy oncolytics2023

Treatment with the PPARα agonist fenofibrate improves the efficacy of CD8

Mohadeseh Hasanpourghadi, Arezki Chekaoui, Sophia Kurian, Raj Kurupati, Robert Ambrose, Wynetta Giles-Davis, Amara Saha, Xu Xiaowei, Hildegund C J Ertl

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy oncolytics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Metabolism of tumor infiltrating T cells.Frontiers in immunology · 2025
    Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mohadeseh HasanpourghadiThe Wistar Institute, Philadelphia, PA 19104, USA.
Arezki ChekaouiThe Wistar Institute, Philadelphia, PA 19104, USA.
Sophia KurianThe Wistar Institute, Philadelphia, PA 19104, USA.
Raj KurupatiThe Wistar Institute, Philadelphia, PA 19104, USA.
Robert AmbroseThe Wistar Institute, Philadelphia, PA 19104, USA.
Wynetta Giles-DavisThe Wistar Institute, Philadelphia, PA 19104, USA.
Amara SahaThe Wistar Institute, Philadelphia, PA 19104, USA.
Xu XiaoweiPathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Hildegund C J ErtlThe Wistar Institute, Philadelphia, PA 19104, USA.
The Wistar Institute · USHospital of the University of Pennsylvania · US

Funding

Quantitative dual-mode scanner for breast cancer therapyR41CA180191 · NCI · PET/X, LLC · PI HUNTER, WILLIAM COULIS JASON · 2013 to 2014
$407k
NCI NIH HHS R41 CA180191
6 · The paper itself

Abstract

Adoptive transfer of tumor antigen-specific CD8

Indexed as

melanomaPDX mouse modelPPARα agonist treatmentT cell metabolismtumor antigen-specific T cells

Identifiers

PMID38075243
PMCPMC10701456
OpenAlexW4388294133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.