Evidence map›Paper›PMID 38075073›Full record

Trial reportFrontiers in endocrinology2023

Effects of the Zishen Yutai Pill compared with placebo on pregnancy outcomes among women in a fresh embryo transfer cycle: a

Xiaoli Chen, Yu Li, Jiewen Zhou, Xuemei Wei, Na Ning, Qiuling Huang, Xiufei Pang, Dongzi Yang

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xiaoli ChenCenter for Reproductive Medicine, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, China.
Yu LiCenter for Reproductive Medicine, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, China.
Jiewen ZhouThe First Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.
Xuemei WeiGuangdong Development Engineering Laboratory of Southern Chinese Herbal Drugs, Guangzhou, China.
Na NingGuangdong Development Engineering Laboratory of Southern Chinese Herbal Drugs, Guangzhou, China.
Qiuling HuangGuangdong Development Engineering Laboratory of Southern Chinese Herbal Drugs, Guangzhou, China.
Xiufei PangGuangdong Development Engineering Laboratory of Southern Chinese Herbal Drugs, Guangzhou, China.
Dongzi YangCenter for Reproductive Medicine, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, China.
Sun Yat-sen Memorial Hospital · CNGuangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess whether the administration of Zishen Yutai Pill (ZYP) could improve the pregnancy outcomes in different subgroups of women undergoing fresh embryo transfer cycles. Materials and methods: This is a Results: ZYP showed a significantly higher clinical pregnancy rates than placebo in the ITT population. Detailed subgroup analyses were conducted in subgroup in advanced maternal age (AMA, ≥ 35 years old) and overweight/obese patients (BMI > 24), due to the clinical importance and statistical results. In these subgroups, baseline characteristics were similar between two arms (all P > 0.05). Significantly elevated clinical pregnancy rates were observed in ZYP cohort (both P < 0.05) compared with the placebo group. Results also showed that ZYP treatment resulted in significantly higher rates of implantation, biochemical pregnancy in AMA or overweight/obese patients in ITT analysis (all P < 0.05). Conclusions: The current Clinical trial registration: Chictr.org.cn, ChictrTRC-14004494.

Indexed as

OverweightPregnancy OutcomeAdultDrugs, Chinese HerbalEmbryo TransferFemaleHumansInfant, NewbornObesityPregnancyDrugs, Chinese HerbalZishen Yutaiembyro transferin vitro ferilizaionsubgroup analysistradtional chinese medicineZishen Yutai pill

Identifiers

PMID38075073
PMCPMC10703301
OpenAlexW4388940379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.