Evidence map›Paper›PMID 38075070›Full record

ReviewFrontiers in endocrinology2023

Pancreas and islet morphology in cystic fibrosis: clues to the etiology of cystic fibrosis-related diabetes.

Sarah S Malik, Diksha Padmanabhan, Rebecca L Hull-Meichle

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06837181 (Studying the Presence of CFRD Complications With Thoughtful Recruitment), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06837181 recruitingnot on this mapstarted 2025, after this paper: background citation

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

TypeobservationalSponsorJaeb Center for Health ResearchRan2025 to 2028Enrolled200ConditionsCystic Fibrosis (CF), Cystic Fibrosis-related Diabetes, Diabetes, RetinopathyArmsobservational study
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Impact of Genetics on Endocrine Manifestations of Cystic Fibrosis.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Approach to the Patient With Pancreatogenic Diabetes.The Journal of clinical endocrinology and metabolism · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Role of the Pancreatic Islet Microvasculature in Health and Disease.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Sarah S MalikDepartment of Pharmacology, University of Washington, Seattle, WA, United States.
Diksha PadmanabhanResearch Service, Veterans Affairs Puget Sound Health Care System, Seattle, WA, United States.
Rebecca L Hull-MeichleDepartment of Pharmacology, University of Washington, Seattle, WA, United States.
Seattle Institute for Biomedical and Clinical Research · USUniversity of Washington · USVA Puget Sound Health Care System · US

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss, Lucas R Hoffman · 2010 to 2026
$21.4M
Pharmacological Sciences SupplementT32GM007750 · NIGMS · UNIVERSITY OF WASHINGTON · PI ATKINS, WILLIAM M · 1985 to 2023
$12.6M
BLRD VA I01 BX004063NIDDK NIH HHS P30 DK089507NIGMS NIH HHS T32 GM007750
6 · The paper itself

Abstract

Cystic fibrosis (CF) is a multi-organ disease caused by loss-of-function mutations in

Indexed as

Cystic FibrosisDiabetes MellitusIslets of LangerhansPancreasAdultCystic Fibrosis Transmembrane Conductance RegulatorHumansCystic Fibrosis Transmembrane Conductance Regulatorbeta cellcystic fibrosiscystic fibrosis-related diabetesductexocrine pancreasisletmicroenvironment

Identifiers

PMID38075070
PMCPMC10704027
OpenAlexW4388939898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.