ReviewInfectious medicine2022
Host immunity and vaccine development against Dengue virus.
Review in Infectious medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Worldwide distribution, symptoms and diagnosis of the coinfections between malaria and arboviral diseases: a systematic review.Memorias do Instituto Oswaldo Cruz · 2024Pooled it
- TTV Viremia and Immune Responses Following Vaccination Against Mpox and Dengue Viruses.Vaccines · 2026Article
- Co-circulation of Plasmodium vivax and Arboviruses in the Brazil-French Guiana Border.Revista da Sociedade Brasileira de Medicina Tropical · 2026Article
- Review
- Recommendations for dengue vaccine implementation in the elderly population.Therapeutic advances in vaccines and immunotherapy · 2025Review
- Analysis of the correlation between climatic variables and Dengue cases in the city of Alagoinhas/BA.Scientific reports · 2023Article
- Identification of new inhibitors of NS5 from dengue virus using saturation transfer difference (STD-NMR) and molecular docking studies.RSC advances · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue is one of the most prevalent and influential mosquito-borne viral infections in the world. According to 1 modeling estimate, the World Health Organization indicated that the annual cases of dengue virus (DENV) infection are as high as 390 million, placing more than half of the global population at risk. Despite its overwhelming prevalence, there is still no effective control method for containing this rapidly spreading disease. The only vaccine currently licensed for use is Dengvaxia, a tetravalent chimeric vaccine developed by Sanofi Pasteur in 2019. However, this vaccine fails to elicit a balanced immune response against all 4 serotypes of DENV and causes severe side effects in seronegative vaccine recipients. Vaccines naturally stimulate cellular and humoral immune responses, which are crucial for vaccine immunogenicity and clinical protection. This article focuses on these 2 immune responses triggered by DENV and their relationship with the efficacy of various vaccine candidates. This information will help us understand the vaccine immune response and relevant clinical protective efficacy further, providing insights into the development of new vaccines. Finally, we summarize feasible approaches for future vaccine development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.