ArticleInfectious medicine2022
Disseminated herpes simplex infection induced hepatitis during pregnancy mimicking HELLP syndrome, a diagnostic challenge.
Article in Infectious medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 1 citations in OpenAlex.
- Genital Herpes Simplex Virus (HSV) Infection During Pregnancy - Recommendations of the Working Group on Obstetrics and Prenatal Medicine (AGG - Section on Maternal Disorders).Geburtshilfe und Frauenheilkunde · 2026Article
- Herpesvirus-associated diseases: biomarkers and advancements in clinical research.Virology journal · 2025Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The disseminated herpes simplex virus 2 (HSV-2) carries a high mortality rate in pregnant women if left unrecognized. It often presents as unrelieved fever and hepatitis. Diagnosis is challenging due to vague symptoms and potential overlap with other conditions. Pregnancy is a risk factor as it conforms to a partially immunocompromised state. Dissemination to the brain could be devastating, and the treatment requires intravenous antivirals like acyclovir. Fetal outcomes are variable based on previous case reports. We present a case of young female gravida 1 para 1 who presented with disseminated HSV infection mimicking HELLP (Hemolysis, Elevated Liver enzymes, and Low Platelets) syndrome. She responded well to intravenous acyclovir, and the fetus had a viable outcome at the 26th week of gestation. Early diagnosis can prevent progression to fulminant liver failure and the need for a liver transplant.
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Registered trials
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