Evidence map›Paper›PMID 38074790›Full record

ArticleRadiology. Artificial intelligence2023

A Super-Resolution Diffusion Model for Recovering Bone Microstructure from CT Images.

Trevor J Chan, Chamith S Rajapakse

Abstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. MUSiK: An Open Source Simulation Library for 3D Multi-View Ultrasound.IEEE transactions on bio-medical engineering · 2026
    Article
  3. Review
  4. Article
  5. Super-resolution of biomedical volumes with 2D supervision.Conference on Computer Vision and Pattern Recognition Workshops. IEEE Computer Society Conference on Computer Vision and Pattern Recognition. Workshops · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Trevor J ChanFrom the Departments of Bioengineering (T.J.C.), Radiology (T.J.C., C.S.R.), and Orthopedic Surgery (C.S.R.), University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104-6243.ORCID https://orcid.org/0000-0003-2327-5050
Chamith S RajapakseFrom the Departments of Bioengineering (T.J.C.), Radiology (T.J.C., C.S.R.), and Orthopedic Surgery (C.S.R.), University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104-6243.ORCID 0000-0002-9247-833X

Funding

MRI Assessment of Hip Fracture Risk and Therapy Response in HIV/HCV CoinfectionR01AR076392 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI RAJAPAKSE, CHAMITH SUDESH · 2019 to 2023
$2.7M
NIAMS NIH HHS R01 AR076392
6 · The paper itself

Abstract

Purpose: To use a diffusion-based deep learning model to recover bone microstructure from low-resolution images of the proximal femur, a common site of traumatic osteoporotic fractures. Materials and Methods: Training and testing data in this retrospective study consisted of high-resolution cadaveric micro-CT scans ( Results: Compared with popular deep learning baselines, the proposed model exhibited greater accuracy (mean ICC of proposed model, 0.92 vs ICC of next best method, 0.83) and lower bias (mean difference in means, 3.80% vs 10.00%, respectively) across the physiologic metrics. Two gradient-based image quality metrics strongly correlated with accuracy across structural and mechanical criteria ( Conclusion: The proposed method may enable accurate measurements of bone structure and strength with a radiation dose on par with current clinical imaging protocols, improving the viability of clinical CT for assessing bone health.

Indexed as

CTImage PostprocessingLong BonesPrognosisQuantificationRadiation EffectsSemisupervised LearningSkeletal-Appendicular

Identifiers

PMID38074790
PMCPMC10698592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.