Evidence map›Paper›PMID 38074785›Full record

ArticleRadiology. Artificial intelligence2023

External Evaluation of a Mammography-based Deep Learning Model for Predicting Breast Cancer in an Ethnically Diverse Population.

Olasubomi J Omoleye, Anna E Woodard, Frederick M Howard, Fangyuan Zhao, Toshio F Yoshimatsu, Yonglan Zheng, Alexander T Pearson, Maksim Levental, Benjamin S Aribisala, Kirti Kulkarni and 4 more

Open access · greenAbstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Integrating multi-omics data for next-generation cancer research and precision medicine.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
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  5. Article
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  8. Hierarchical diagnosis of breast phyllodes tumors enabled by deep learning of ultrasound images: a retrospective multi-center study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  9. Review
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Olasubomi J OmoleyeFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).ORCID https://orcid.org/0000-0002-6922-9298
Anna E WoodardFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).ORCID 0000-0002-8640-5417
Frederick M HowardFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).
Fangyuan ZhaoFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).
Toshio F YoshimatsuFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).ORCID 0000-0003-2674-8159
Yonglan ZhengFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).ORCID 0000-0001-6597-7072
Alexander T PearsonFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).
Maksim LeventalFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).
Benjamin S AribisalaFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).
Kirti KulkarniFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).
Gregory S KarczmarFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).ORCID 0000-0002-2455-5858
Olufunmilayo I OlopadeFrom the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).ORCID 0000-0002-9936-1599
Hiroyuki Abe *From the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).
Dezheng Huo *From the Center for Clinical Cancer Genetics and Global Health, Department of Medicine (O.J.O., A.E.W., T.F.Y., Y.Z., B.S.A., O.I.O.), Data Science Institute (A.E.W.), Division of Hematology/Oncology, Department of Medicine (F.M.H., A.T.P.), Department of Public Health Sciences (F.Z., D.H.), Department of Computer Science (M.L.), and Department of Radiology (K.K., G.S.K., H.A.), The University of Chicago, 5841 S Maryland Ave, MC 2000, Chicago, IL 60637; Department of Computer Science, Lagos State University, Lagos, Nigeria (B.S.A.).ORCID 0000-0002-4041-1678
Oregon Health & Science University · USMcCrone Research Institute · US

Funding

Developing an Oncology Workforce for the 21st Century - Renewal 01K12CA139160 · NCI · UNIVERSITY OF CHICAGO · PI OLOPADE, OLUFUNMILAYO F., SMITH, SONALI · 2010 to 2024
$10.6M
UChicago Interdisciplinary Cancer Health Disparities SPOREP20CA233307 · NCI · UNIVERSITY OF CHICAGO · PI HUO, DEZHENG, NANDA, RITA · 2018 to 2020
$3.4M
Multiscale Computational Models Guided By Emerging Cellular Dynamics Quantification For Predicting Optimum Immune Checkpoint And Targeted Therapy SchedulesU01CA243075 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JACKSON, TRACHETTE · 2020 to 2024
$2.6M
Deep learning for oral premalignancy evaluationR56DE030958 · NIDCR · UNIVERSITY OF CHICAGO · PI PEARSON, ALEXANDER THOMAS · 2021 to 2021
$331k
NCI NIH HHS K12 CA139160NCI NIH HHS P20 CA233307NCI NIH HHS U01 CA243075NIDCR NIH HHS R56 DE030958
6 · The paper itself

Abstract

Purpose: To externally evaluate a mammography-based deep learning (DL) model (Mirai) in a high-risk racially diverse population and compare its performance with other mammographic measures. Materials and Methods: A total of 6435 screening mammograms in 2096 female patients (median age, 56.4 years ± 11.2 [SD]) enrolled in a hospital-based case-control study from 2006 to 2020 were retrospectively evaluated. Pathologically confirmed breast cancer was the primary outcome. Mirai scores were the primary predictors. Breast density and Breast Imaging Reporting and Data System (BI-RADS) assessment categories were comparative predictors. Performance was evaluated using area under the receiver operating characteristic curve (AUC) and concordance index analyses. Results: Mirai achieved 1- and 5-year AUCs of 0.71 (95% CI: 0.68, 0.74) and 0.65 (95% CI: 0.64, 0.67), respectively. One-year AUCs for nondense versus dense breasts were 0.72 versus 0.58 ( Conclusion: A mammography DL model showed good performance in a high-risk external dataset enriched for African American patients, benign breast disease, and

Indexed as

BreastCancerComputer ApplicationsConvolutional Neural NetworkDeep Learning AlgorithmsEpidemiologyInformaticsMachine LearningMammographyOncologyRadiomics

Identifiers

PMID38074785
PMCPMC10698602
OpenAlexW4385287108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.