SynthesisFrontiers in public health2023
Unraveling the link between hypertension and depression in older adults: a meta-analysis.
Synthesis in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 29 citations in OpenAlex.
- Antihypertensive treatment and adverse psychiatric reactions in primary health care.Journal of human hypertension · 2026Article
- Hypertension and depression coexistence and its association with frailty in older adults: a cross-sectional study.Dementia & neuropsychologia · 2026Article
- Sociodemographic factors associated with depressive symptoms and self-care agency capacity in hypertensive older adults from Loja, Ecuador: a cross-sectional study.Frontiers in public health · 2026Article
- The Overlooked Driver of Hypertension: Mental Stress at the Crossroad of Cardiology and Psychiatry.Current atherosclerosis reports · 2025Review
- Non-pharmacological and psychosocial interventions for comorbid hypertension and depression: a scoping review.BMJ open · 2025Article
- The allostatic triage model of psychopathology (ATP Model): How reallocation of brain energetic resources under stress elicits psychiatric symptoms.Neuroscience and biobehavioral reviews · 2025Review
- Stress, Anxiety, and Self-Efficacy in Hypertension: Evidence from a Romanian Case-Control Study.Diseases (Basel, Switzerland) · 2025Article
- Prevalence and Associated Factors of Depression Among Elderly Hypertensive Patients in Vietnam.Geriatrics (Basel, Switzerland) · 2025Article
- Independent and joint associations of hypertension and depression with cardiovascular diseases and all-cause mortality: a population-based cohort study.Journal of human hypertension · 2025Article
- Association of Emotion, Sleep Quality With Hypertension and Complications in the Elderly Population.Brain and behavior · 2025Article
- Prevalence of depression and its network structure and association with quality of life in older adults with hypertension: findings of a national survey.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2025Article
- CHARLS insights into the impact of dual interactions of chronic diseases on depression in middle-aged and elderly individuals.Scientific reports · 2025Article
- A predictive model for depression risk in individuals with hypertension: evidence from NHANES 2007-2020.BMC public health · 2025Article
- A vascular endothelial cell, neuron, and microglia tri-culture model to study hypertension-related depression.Frontiers in cellular neuroscience · 2025Article
- Research on the social integration and depression risk of middle-aged and older adults with multiple chronic conditions in China.Frontiers in public health · 2025Article
- Nonlinear associations of depression and sleep duration with cognitive impairment in older adults with hypertension: findings from a national survey.Frontiers in aging neuroscience · 2025Article
- The mediating role of self-care self-efficacy in the relationship between health behavior and psychological wellbeing among community-dwelling older adults with hypertension.Frontiers in public health · 2025Article
- Exploring the Causal Relationships and Mediating Factors Between Mental Disorders and Hypertension: A Multivariable Mendelian Randomization Study.Global heart · 2025Article
- Renal interoception in health and disease.Autonomic neuroscience : basic & clinical · 2024Review
- Intervention strategies for management of comorbid depression among individuals with hypertension: a scoping review protocol.BMJ open · 2024Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To perform a meta-analyses to understand the current status of and risk factors for depression in older adults with hypertension. Methods: Eight electronic databases and two clinical trial registries were searched to identify studies examining the incidence of and risk factors for depression among older adults with hypertension. The databases were searched from inception to June 2023. The included studies were evaluated using the Newcastle-Ottawa scale and the evaluation tool recommended by the Agency for Health care Research and Quality. Results: A total of 18 studies with 29,694 patients were included. Meta-analysis results showed that the prevalence of depression in older adults with hypertension was 29%. The risk factors for depression among this population included sex [OR value 95% confidence interval 2.24 (1.32, 3.82)], education level [OR 95% CI 1.79 (1.02, 3.14)], residence [OR 95% CI 1.37 (1.24, 1.52)], comorbidities [OR 95% CI 1.79 (1.69, 1.90)], hypertension classification [OR 95% CI 2.81 (1.79, 4.42)], marital status [OR 95% CI 1.50 (1.33, 1.69)], sleep status [OR 95% CI 2.86 (2.21, 3.69)], activity limitation [OR 95% CI 3.42 (2.84, 4.13)], drinking [OR 95% CI 2.25 (1.58, 3.19)], social support [OR 95% CI 3.26 (2.42, 4.41)], living alone [OR 95% CI 1.79 (1.57, 2.04)], stressful events [OR 95% CI 1.62 (1.39, 1.90)], and course of diseases [OR 95% CI 3.23 (2.10, 4.97)]. Conclusion: The incidence of depression in older adults with hypertension is high, and there are many risk factors. Clinical health care professionals should intervene early to target the above risk factors to reduce the incidence of depression in older adults with hypertension worldwide. Systematic review registration: PROSPERO (york.ac.uk), identifier [CRD42023417106].
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