Evidence map›Paper›PMID 38074016›Full record

ArticleCureus2023

Extragonadal Nongestational Choriocarcinoma With a Widespread Metastasis in a Young Female: A Case Report and Literature Analysis With a Focus on Unmet Needs.

Amitabh Kumar Upadhyay, Shashank Shekhar, Reetal Singh, Abhishek Kumar, Vanita Pandey, Aaditya Prakash

Abstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amitabh Kumar UpadhyayMedical Oncology, Tata Main Hospital, Jamshedpur, IND.
Shashank ShekharMedical Oncology, Meherbai Tata Memorial Hospital, Jamshedpur, IND.
Reetal SinghMedical Oncology, Meherbai Tata Memorial Hospital, Jamshedpur, IND.
Abhishek KumarNuclear Medicine, Tata Main Hospital, Jamshedpur, IND.
Vanita PandeyPathology, Meherbai Tata Memorial Hospital, Jamshedpur, IND.
Aaditya PrakashRadiation Oncology, Tata Main Hospital, Jamshedpur, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Choriocarcinoma is a highly aggressive malignant tumor that occurs due to the formation of an abnormal trophoblast. Choriocarcinoma is classified into gestational (GC) and nongestational (NGC) subtypes. The majority of nongestational diseases are limited to ovaries. Extragonadal NGC is a sporadic occurrence and a diagnostic and therapeutic dilemma. Here, we present a young 24-year-old female who presented with a widespread metastatic disease to the brain, bilateral kidneys, lungs, liver, pancreas, and small bowel. She was diagnosed with extragonadal NGC, probably originating from her kidneys. She responded poorly to standard first-, second-, and third-line chemotherapies. Detailed literature analysis with various aspects of pathogenesis, diagnostic criteria, clinical presentation, and treatment options are discussed. There is an unmet need for further research and consensus on many aspects of this rare disease.

Indexed as

beta-hcgchoriocarcinomaextragonadalnongestationalunmet need

Identifiers

PMID38074016
PMCPMC10701193

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.