Evidence map›Paper›PMID 38073670›Full record

ArticleCase reports in women's health2023

Intrauterine fetal death due to fetal intracranial hemorrhage associated with maternal vitamin K deficiency: A case report.

Koya Yasuda, Soichiro Obata, Eita Kumagai, Takayoshi Iijima, Masafumi Yamamoto, Etsuko Miyagi, Shigeru Aoki

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in women's health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Vitamin K Deficiency: Diagnosis and Management.Annals of laboratory medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Koya YasudaPerinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, Japan.
Soichiro ObataPerinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, Japan.
Eita KumagaiDepartment of Pathology, Yokohama City University Medical Center, Yokohama, Japan.
Takayoshi IijimaPerinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, Japan.
Masafumi YamamotoPerinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, Japan.
Etsuko MiyagiDepartment of Obstetrics and Gynecology, Yokohama City University Hospital, Yokohama, Japan.
Shigeru AokiPerinatal Center for Maternity and Neonates, Yokohama City University Medical Center, Yokohama, Japan.
Yokohama City University · JPYokohama City University Medical Center · JPYokohama City University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin K deficiency can cause coagulopathy; therefore, supplementation is recommended to prevent intracranial hemorrhage in newborns. Some reports have shown that maternal vitamin K deficiency is associated with intracranial hemorrhage in the fetus. However, no clear guidelines exist for the diagnosis and treatment of maternal vitamin K deficiency to prevent fetal intracranial hemorrhage. We report a case of intrauterine fetal death due to intracranial hemorrhage associated with maternal vitamin K deficiency resulting from hyperemesis gravidarum. In this case, maternal protein induced by vitamin K absence II (PIVKA-II) was high at the time of intrauterine fetal death. Therefore, measuring maternal PIVKA-II levels in high-risk cases may help determine the timing of therapeutic interventions for vitamin K deficiency during pregnancy.

Indexed as

Hyperemesis gravidarumIntracranial hemorrhagePIVKA-IIPregnancyVitamin K deficiency

Identifiers

PMID38073670
PMCPMC10700151
OpenAlexW4388802324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.