Evidence map›Paper›PMID 38073629›Full record

ReviewFrontiers in neurology2023

Radiological markers of neurological manifestations of post-acute sequelae of SARS-CoV-2 infection: a mini-review.

Olivia Cull, Lina Al Qadi, Josiane Stadler, Mykella Martin, Antonios El Helou, Jeffrey Wagner, Danica Maillet, Ludivine Chamard-Witkowski

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06424652 (Effect of Physiologic Insulin Administration on Cognition), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06424652 nacompletednot on this mapstarted 2024, after this paper: background citation

Effect of Physiologic Insulin Administration on Cognition

TypeinterventionalSponsorPennington Biomedical Research CenterRan2024 to 2025Enrolled1ConditionsAlzheimer DiseaseArmsBlood draws, Hyperinsulinemic Euglycemic Clamp Technique Insulin Sensitivity test, Resting Metabolic Rate (RMR)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Olivia Cull *Centre de formation médicale du Nouveau Brunswick, University of Sherbrooke, Moncton, NB, Canada.
Lina Al Qadi *Centre de formation médicale du Nouveau Brunswick, University of Sherbrooke, Moncton, NB, Canada.
Josiane StadlerCentre de formation médicale du Nouveau Brunswick, University of Sherbrooke, Moncton, NB, Canada.
Mykella MartinCentre de formation médicale du Nouveau Brunswick, University of Sherbrooke, Moncton, NB, Canada.
Antonios El HelouNew Brunswick Center for Precision Medicine, Moncton, NB, Canada.
Jeffrey WagnerFaculty of Medicine, Dalhousie University, Halifax Regional Municipality, Halifax, NS, Canada.
Danica MailletVitalité Health Network, Dr. Georges-L.-Dumont University Hospital Centre, Moncton, NB, Canada.
Ludivine Chamard-WitkowskiNew Brunswick Center for Precision Medicine, Moncton, NB, Canada.
University of New Brunswick · CADalhousie University · CADr. Georges-L.-Dumont University Hospital Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neurological impact of COVID-19 is a rising concern among medical professionals, as patients continue to experience symptoms long after their recovery. This condition, known as neurological post-acute sequelae of COVID-19 (Neuro-PASC), can last for more than 12 weeks and includes symptoms such as attention disorders, brain fog, fatigue, and memory loss. However, researchers and health professionals face significant challenges in understanding how COVID-19 affects the brain, limiting the development of effective prevention and treatment strategies. In this mini-review, we provide readers with up-to-date information on the imaging techniques currently available for measuring the neurological impact of post-SARS-CoV-2 infection. Our search of PubMed and Google Scholar databases yielded 38 articles on various brain imaging techniques, including structural MRI (magnetic resonance imaging), functional MRI, diffusion MRI, susceptibility-weighted imaging, SPECT (single-photon emission computed tomography) imaging, and PET (positron emission tomography) imaging. We also discuss the optimal usage, limitations, and potential benefits of these techniques. Our findings show that various cerebral imaging techniques have been evaluated to identify a reliable marker for Neuro-PASC. For instance,

Indexed as

fMRIimagingMRINeuro-PASCPET/CT scanpost-COVIDSPECT (single-photon emission computed tomography)

Identifiers

PMID38073629
PMCPMC10704137
OpenAlexW4388976800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.