Evidence map›Paper›PMID 38073320›Full record

ArticlePediatrics2024

Disparities in Pharmacologic Restraint for Children Hospitalized in Mental Health Crisis.

Ryan M Wolf, Matt Hall, Derek J Williams, James W Antoon, Alison R Carroll, Kelsey A B Gastineau, My-Linh Ngo, Alison Herndon, Sarah Hart, Deanna S Bell and 1 more

Abstract read
In one paragraph

Article in Pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ryan M WolfDepartment of Pediatrics, Division of Hospital Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt and Vanderbilt University Medical Center, Nashville, Tennessee.
Matt HallChildren's Hospital Association, Lenexa, Kansas.
Derek J WilliamsDepartment of Pediatrics, Division of Hospital Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt and Vanderbilt University Medical Center, Nashville, Tennessee.
James W AntoonDepartment of Pediatrics, Division of Hospital Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt and Vanderbilt University Medical Center, Nashville, Tennessee.
Alison R CarrollDepartment of Pediatrics, Division of Hospital Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt and Vanderbilt University Medical Center, Nashville, Tennessee.
Kelsey A B GastineauDepartment of Pediatrics, Division of Hospital Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt and Vanderbilt University Medical Center, Nashville, Tennessee.
My-Linh NgoDepartment of Pediatrics, Division of Hospital Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt and Vanderbilt University Medical Center, Nashville, Tennessee.
Alison HerndonDepartment of Pediatrics, Division of Hospital Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt and Vanderbilt University Medical Center, Nashville, Tennessee.
Sarah HartDepartment of Pediatrics, Division of Hospital Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt and Vanderbilt University Medical Center, Nashville, Tennessee.
Deanna S BellDepartment of Pediatrics, Division of Hospital Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt and Vanderbilt University Medical Center, Nashville, Tennessee.
David P JohnsonDepartment of Pediatrics, Division of Hospital Medicine, Monroe Carell Jr Children's Hospital at Vanderbilt and Vanderbilt University Medical Center, Nashville, Tennessee.

Funding

Institutional Career Development CoreKL2TR002245 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$9.3M
Learning Health System training program: PROgRESS--Patient/ pRactice Outcomes and Research in Effectiveness and Systems ScienceT32HS026122 · AHRQ · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GRIJALVA, CARLOS G, ROUMIE, CHRISTIANNE L. · 2018 to 2024
$3.5M
Oseltamivir Use and Risk of Serious Neuropsychiatric Adverse Events in ChildrenK23AI168496 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ANTOON, JAMES W · 2022 to 2025
$740k
AHRQ HHS T32 HS026122NCATS NIH HHS KL2 TR002245NIAID NIH HHS K23 AI168496
6 · The paper itself

Abstract

BACKGROUND AND

objectivesChildren hospitalized with a mental health crisis often receive pharmacologic restraint for management of acute agitation. We examined associations between pharmacologic restraint use and race and ethnicity among children admitted for mental health conditions to acute care nonpsychiatric children's hospitals.

methodsWe performed a retrospective cohort study of children (aged 5-≤18 years) admitted for a primary mental health condition from 2018 to 2022 at 41 US children's hospitals. Pharmacologic restraint use was defined as parenteral administration of medications for acute agitation. The association of race and ethnicity and pharmacologic restraint was assessed using generalized linear multivariable mixed models adjusted for clinical and demographic factors. Stratified analyses were performed based on significant interaction analyses between covariates and race and ethnicity.

resultsThe cohort included 61 503 hospitalizations. Compared with non-Hispanic Black children, children of non-Hispanic White (adjusted odds ratio [aOR], 0.81; 95% confidence interval [CI], 0.72-0.92), Asian (aOR, 0.82; 95% CI, 0.68-0.99), or other race and ethnicity (aOR, 0.68; 95% CI, 0.57-0.82) were less likely to receive pharmacologic restraint. There was no significant difference with Hispanic children. When stratified by sex, racial/ethnic differences were magnified in males (aORs, 0.49-0.68), except for Hispanic males, and not found in females (aORs, 0.83-0.93). Sensitivity analysis revealed amplified disparities for all racial/ethnic groups, including Hispanic youth (aOR, 0.65; 95% CI, 0.47-0.91).

conclusionsNon-Hispanic Black children were significantly more likely to receive pharmacologic restraint. More research is needed to understand reasons for these disparities, which may be secondary to implicit bias and systemic and interpersonal racism.

Indexed as

EthnicityHealthcare DisparitiesMental HealthRacial GroupsAdolescentChildChild, PreschoolFemaleHumansMaleRetrospective Studies

Identifiers

PMID38073320
PMCPMC10764008

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.