Evidence map›Paper›PMID 38071587›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2024

Early-Frame [

Ates Fettahoglu, Moss Zhao, Mehdi Khalighi, Hillary Vossler, Maria Jovin, Guido Davidzon, Michael Zeineh, Fernando Boada, Elizabeth Mormino, Victor W Henderson and 3 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Evaluation of early-phaseJournal of Alzheimer's disease : JAD · 2025
    Article
  4. [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  5. [European journal of nuclear medicine and molecular imaging · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Ates FettahogluDepartment of Radiology, Stanford University, Stanford, California.
Moss ZhaoDepartment of Radiology, Stanford University, Stanford, California.
Mehdi KhalighiDepartment of Radiology, Stanford University, Stanford, California.
Hillary VosslerDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, California; and.
Maria JovinDepartment of Radiology, Stanford University, Stanford, California.
Guido DavidzonDepartment of Radiology, Stanford University, Stanford, California.
Michael ZeinehDepartment of Radiology, Stanford University, Stanford, California.
Fernando BoadaDepartment of Radiology, Stanford University, Stanford, California.
Elizabeth MorminoDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, California; and.
Victor W HendersonDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, California; and.
Michael MoseleyDepartment of Radiology, Stanford University, Stanford, California.
Kevin T ChenDepartment of Biomedical Engineering, National Taiwan University, Taipei, Taiwan chenkt@ntu.edu.tw.
Greg ZaharchukDepartment of Radiology, Stanford University, Stanford, California.
Stanford University · USCardiovascular Institute of the South · USNational Taiwan University of Science and Technology · TWYale University · US

Funding

Stanford Alzheimer's Disease Research CenterAdmin Supp: Developing iPSC models for AD and PDP30AG066515 · NIA · STANFORD UNIVERSITY · PI Michael D Greicius · 2020 to 2026
$29.0M
Training and DisseminationP41EB015891 · NIBIB · STANFORD UNIVERSITY · PI GLOVER, GARY H · 2012 to 2019
$10.7M
Iron as an Imaging Biomarker for Inflammation in ADR01AG061120 · NIA · STANFORD UNIVERSITY · PI ZEINEH, MICHAEL M · 2019 to 2023
$3.5M
Cerebrovascular Reserve Imaging with Simultaneous PET/MRI Using Arterial Spin Labeling and Deep LearningR01EB025220 · NIBIB · STANFORD UNIVERSITY · PI ZAHARCHUK, GREGORY GEORGE · 2018 to 2021
$2.8M
High-resolution imaging of hippocampal mechanisms in age-related memory decline.R01AG048076 · NIA · STANFORD UNIVERSITY · PI WAGNER, ANTHONY D · 2014 to 2018
$1.9M
The impact of early medial temporal lobe Tau in human cognitive agingR21AG058859 · NIA · STANFORD UNIVERSITY · PI MORMINO, ELIZABETH · 2018 to 2019
$432k
Generalizable Deep Learning Networks for Dual-tracer Amyloid/Tau PET/MRI Imaging of Alzheimer's DiseaseK99AG068310 · NIA · STANFORD UNIVERSITY · PI CHEN, KEVIN TZE-HSIANG · 2021 to 2021
$101k
NIA NIH HHS K99 AG068310NIA NIH HHS P30 AG066515NIA NIH HHS R01 AG048076NIA NIH HHS R01 AG061120NIA NIH HHS R21 AG058859NIBIB NIH HHS P41 EB015891NIBIB NIH HHS R01 EB025220
6 · The paper itself

Abstract

Cerebral blood flow (CBF) may be estimated from early-frame PET imaging of lipophilic tracers, such as amyloid agents, enabling measurement of this important biomarker in participants with dementia and memory decline. Although previous methods could map relative CBF, quantitative measurement in absolute units (mL/100 g/min) remained challenging and has not been evaluated against the gold standard method of [

Indexed as

Aniline CompoundsCognitive DysfunctionDementiaStilbenesBrainCerebrovascular CirculationFemaleHumansMagnetic Resonance ImagingMaleOxygen RadioisotopesPositron-Emission TomographyWater4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbeneAniline CompoundsOxygen RadioisotopesStilbenesWater[18F]florbetaben PETcerebral blood flowPET/MRIphase-contrast MRI

Identifiers

PMID38071587
PMCPMC10858379
OpenAlexW4389454413

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.