Trial reportJournal of neurology, neurosurgery, and psychiatry2024
Improved naming in patients with Broca's aphasia with tDCS.
Trial report in Journal of neurology, neurosurgery, and psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07688551 (Transcranial Direct Current Stimulation to Treat Aphasia), which is not on this map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Transcranial Direct Current Stimulation to Treat Aphasia: A Superiority Study
Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- tDCS and Speech Therapy in Aphasia Treatment: A Multicenter Comparative Study of Efficacy.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- Beyond the Plateau: Repeated Treatment Opportunities Are Associated with Improved Naming in Chronic Post-Stroke Aphasia.Brain sciences · 2026Article
- Improving Lexicosemantic Impairments in Post-Stroke Aphasia Using rTMS Targeting the Right Anterior Temporal Lobe.Brain sciences · 2026Article
- Neuromodulation for post-stroke aphasia rehabilitation: established cortical stimulation and emerging network-based targets.Frontiers in human neuroscience · 2026Review
- Advances in Neuromodulation Techniques for Aphasia Rehabilitation: A Comprehensive Review.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- The Use of Neurologic Music Therapy in Post-Stroke Aphasia Recovery: A Case Report on Linguistic Improvements and fMRI Correlates.Journal of clinical medicine · 2025Article
- Behavioral, Functional Imaging, and Neurophysiological Outcomes of Transcranial Direct Current Stimulation and Speech-Language Therapy in an Individual with Aphasia.Brain sciences · 2024Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundLanguage impairment (aphasia) is a common neurological deficit after strokes. For individuals with chronic aphasia (beyond 6 months after the stroke), language improvements with speech therapy (ST) are often limited. Transcranial direct current stimulation (tDCS) is a promising approach to complement language recovery but interindividual variability in treatment response is common after tDCS, suggesting a possible relationship between tDCS and type of linguistic impairment (aphasia type).
methodsThis current study is a subgroup analysis of a randomised controlled phase II futility design clinical trial on tDCS in chronic post-stroke aphasia. All participants received ST coupled with tDCS (n=31) vs sham tDCS (n=39). Confrontation naming was tested at baseline, and 1, 4, and 24 weeks post-treatment.
resultsBroca's aphasia was associated with maximal adjunctive benefit of tDCS, with an average improvement of 10 additional named items with tDCS+ST compared with ST alone at 4 weeks post-treatment. In comparison, tDCS was not associated with significant benefits for other aphasia types
conclusionsThese results indicate that adjuvant tDCS can enhance ST to treat naming in Broca's aphasia, and this may guide intervention approaches in future studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.