Evidence map›Paper›PMID 38071317›Full record

ArticleTranslational psychiatry2023

Using digital phenotyping to capture depression symptom variability: detecting naturalistic variability in depression symptoms across one year using passively collected wearable movement and sleep data.

George D Price, Michael V Heinz, Seo Ho Song, Matthew D Nemesure, Nicholas C Jacobson

Abstract read
In one paragraph

Article in Translational psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

George D PriceCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA. George.Price.GR@dartmouth.edu.ORCID 0000-0002-9164-4973
Michael V HeinzCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.
Seo Ho SongDepartment of Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Matthew D NemesureCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.
Nicholas C JacobsonCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.ORCID 0000-0002-8832-4741

Funding

Treatment Development & Evaluation CoreP30DA029926 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2011 to 2026
$21.5M
Personalized Deep Learning Models of Rapid Changes in Major Depressive Disorder Symptoms using Passive Sensor Data from Smartphones and Wearable DevicesR01MH123482 · NIMH · DARTMOUTH COLLEGE · PI JACOBSON, NICHOLAS CHARLES · 2020 to 2024
$2.6M
Training Program for Quantitative Population Sciences in CancerT32CA134286 · NCI · DARTMOUTH COLLEGE · PI KARAGAS, MARGARET RITA, TOSTESON, TOR D · 2020 to 2024
$1.5M
NCI NIH HHS T32 CA134286NIDA NIH HHS P30 DA029926NIMH NIH HHS R01 MH123482
6 · The paper itself

Abstract

Major Depressive Disorder (MDD) presents considerable challenges to diagnosis and management due to symptom variability across time. Only recent work has highlighted the clinical implications for interrogating depression symptom variability. Thus, the present work investigates how sociodemographic, comorbidity, movement, and sleep data is associated with long-term depression symptom variability. Participant information included (N = 939) baseline sociodemographic and comorbidity data, longitudinal, passively collected wearable data, and Patient Health Questionnaire-9 (PHQ-9) scores collected over 12 months. An ensemble machine learning approach was used to detect long-term depression symptom variability via: (i) a domain-driven feature selection approach and (ii) an exhaustive feature-inclusion approach. SHapley Additive exPlanations (SHAP) were used to interrogate variable importance and directionality. The composite domain-driven and exhaustive inclusion models were both capable of moderately detecting long-term depression symptom variability (r = 0.33 and r = 0.39, respectively). Our results indicate the incremental predictive validity of sociodemographic, comorbidity, and passively collected wearable movement and sleep data in detecting long-term depression symptom variability.

Indexed as

Major Depressive DisorderWearable Electronic DevicesComorbidityDepressionHumans

Identifiers

PMID38071317
PMCPMC10710399

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.