Evidence map›Paper›PMID 38070109›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Preparation Method and In Vitro Characterization of Nanoparticles Sensitive to Tumor Microenvironment.

Naym Blal, Daniela Guarnieri

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Naym BlalDipartimento di Chimica e Biologia "A. Zambelli", Università degli Studi di Salerno, Salerno, Italy.
Daniela GuarnieriDipartimento di Chimica e Biologia "A. Zambelli", Università degli Studi di Salerno, Salerno, Italy. dguarnieri@unisa.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy is considered a powerful clinical strategy aiming to boost the immune system to fight cancer. In this context, nanomaterials (NMs) are uniquely suited to improve the development and the broad implementation of cancer immunotherapies by overcoming several challenges. In fact, NMs can be rationally designed to navigate complex physical barriers, respond to tumor microenvironments, and enhance/modulate immune system activation. Here, we present a method to prepare stimuli-responsive biocompatible nanoparticles (NPs) able to target the tumor microenvironment. Moreover, we describe protocols to characterize the physical-chemical properties of NPs as well as to evaluate their biocompatibility and therapeutic potential in vitro on three-dimensional (3D) tumor spheroids.

Indexed as

NanoparticlesNeoplasmsDrug CarriersDrug Delivery SystemsHumansImmunotherapyTumor MicroenvironmentDrug CarriersBiocompatible nanoparticlesDrug deliveryMMP-sensitive peptidesNanoprecipitationStimuli-responsive nanoparticlesTumor microenvironment

Identifiers

PMID38070109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.