Evidence map›Paper›PMID 38069493›Full record

SynthesisMovement disorders : official journal of the Movement Disorder Society2024

Prevalence and Incidence of Parkinson's Disease in Latin America: A Meta-Analysis.

Dani J Kim, Ana L Isidro-Pérez, Michelle Doering, Juan J Llibre-Rodriguez, Isaac Acosta, Ana M Rodriguez Salgado, Gabriel D Pinilla-Monsalve, Caroline Tanner, Jorge J Llibre-Guerra, Matthew Prina

Abstract readMeta-Analysis
In one paragraph

Synthesis in Movement disorders : official journal of the Movement Disorder Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Global, regional, and national burden of Early-onset Parkinson's disease: A comprehensive analysis and forecast, 1990-2021.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Barriers and Facilitators to Accessing Healthcare for People With Parkinson's Disease in Latin America: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Update: Descriptive epidemiology of Parkinson disease.Parkinsonism & related disorders · 2024
    Review
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dani J KimHealth Service and Population Research Department, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom.ORCID 0000-0002-6605-3338
Ana L Isidro-PérezLaboratory of the Dementias, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Michelle DoeringBernard Becker Medical Library, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Juan J Llibre-RodriguezDementia Research Unit, Medical University of Havana, Havana, Cuba.
Isaac AcostaLaboratory of the Dementias, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
Ana M Rodriguez SalgadoGlobal Brain Health Institute, University of San Francisco California, San Francisco, California, USA.
Gabriel D Pinilla-MonsalveCentre de Recherche, Institut Universitaire de Gériatrie de Montréal, Université de Montréal, Montreal, Quebec, Canada.
Caroline TannerDepartment of Neurology, Weill Institute for Neurosciences, University of California-San Francisco, San Francisco, California, USA.
Jorge J Llibre-GuerraDepartment of Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Matthew PrinaHealth Service and Population Research Department, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom.

Funding

Understanding Alzheimer disease heterogeneity in Hispanic populations.K01AG073526 · NIA · WASHINGTON UNIVERSITY · PI Jorge Jesus Llibre-Guerra · 2022 to 2026
$511k
NIA NIH HHS K01 AG073526
6 · The paper itself

Abstract

backgroundParkinson's disease (PD) is a rapidly growing neurodegenerative disorder, but up-to-date epidemiological data are lacking in Latin America. We sought to estimate the prevalence and incidence of PD and parkinsonism in Latin America.

methodsWe searched Medline, Embase, Scopus, Web of Science, Scientific Electronic Library Online, and Literatura Latino-Americana e do Caribe em Ciências da Saúde or the Latin American and Caribbean Health Science Literature databases for epidemiological studies reporting the prevalence or incidence of PD or parkinsonism in Latin America from their inception to 2022. Quality of studies was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist. Data were pooled via random-effects meta-analysis and analyzed by data source (cohort studies or administrative databases), sex, and age group. Significant differences between groups were determined by meta-regression.

resultsEighteen studies from 13 Latin American countries were included in the review. Meta-analyses of 17 studies (nearly 4 million participants) found a prevalence of 472 (95% CI, 271-820) per 100,000 and three studies an incidence of 31 (95% CI, 23-40) per 100,000 person-years for PD; and seven studies found a prevalence of 4300 (95% CI, 1863-9613) per 100,000 for parkinsonism. The prevalence of PD differed by data source (cohort studies, 733 [95% CI, 427-1255] vs. administrative databases. 114 [95% CI, 63-209] per 100,000, P < 0.01), age group (P < 0.01), but not sex (P = 0.73). PD prevalence in ≥60 years also differed significantly by data source (cohort studies. 1229 [95% CI, 741-2032] vs. administrative databases, 593 [95% CI, 480-733] per 100,000, P < 0.01). Similar patterns were observed for parkinsonism.

conclusionsThe overall prevalence and incidence of PD in Latin America were estimated. PD prevalence differed significantly by the data source and age, but not sex. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Indexed as

Parkinson DiseaseCohort StudiesHumansIncidenceLatin AmericaPrevalenceHispanicsincidenceLatin AmericaParkinson's diseaseprevalence

Identifiers

PMID38069493
PMCPMC10872644

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.