Evidence map›Paper›PMID 38069408›Full record

ArticleInternational journal of molecular sciences2023

miR-195-5p as Regulator of γ-Catenin and Desmosome Junctions in Colorectal Cancer.

Emanuele Piccinno, Viviana Scalavino, Raffaele Armentano, Gianluigi Giannelli, Grazia Serino

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Junction Plakoglobin - A Dual-Role Player in Cancer Biology.International journal of surgery (London, England) · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Identification of a Novel miR-195-5p/PNN Axis in Colorectal Cancer.International journal of molecular sciences · 2024
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Emanuele PiccinnoNational Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy.ORCID 0000-0002-7988-1917
Viviana ScalavinoNational Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy.ORCID 0000-0002-0273-2825
Raffaele ArmentanoNational Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy.ORCID 0000-0003-1661-5504
Gianluigi GiannelliNational Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy.ORCID 0000-0002-5140-8060
Grazia SerinoNational Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, BA, Italy.ORCID 0000-0002-2971-0802
Gastroenterology Hospital "Saverio de Bellis" · IT

Funding

Ministero della Salute Ricerca Corrente 2023
6 · The paper itself

Abstract

Desmosomes play a key role in the regulation of cell adhesion and signaling. Dysregulation of the desmosome complex is associated with the loss of epithelial cell polarity and disorganized tissue architecture typical of colorectal cancer (CRC). The aim of this study was to investigate and characterize the effect of miR-195-5p on desmosomal junction regulation in CRC. In detail, we proposed to investigate the deregulation of miR-195-5p and

Indexed as

Colorectal NeoplasmsMicroRNAsCell Line, TumorCell ProliferationDesmosomesgamma CateninGene Expression Regulation, NeoplasticHumansProtein Serine-Threonine KinasesWnt Signaling Pathwaygamma CateninMicroRNAsMIRN195 microRNA, humanNLK protein, humanProtein Serine-Threonine Kinasescell junctionsCRCdesmosomeJUPmicroRNAmiR-195-5pγ-catenin

Identifiers

PMID38069408
PMCPMC10707010
OpenAlexW4389308247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.