Evidence map›Paper›PMID 38069389›Full record

ArticleInternational journal of molecular sciences2023

Association between Nfr2, HO-1, NF-kB Expression, Plasma ADMA, and Oxidative Stress in Metabolic Syndrome.

Ganka Y Bekyarova, Deyana G Vankova, Valentina H Madjova, Nicolai A Bekyarov, Ayshe S Salim, Diana G Ivanova, Stefka M Stoeva, Daniela I Gerova, Yoana D Kiselova-Kaneva

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. International journal of molecular sciences · 2025
    Article
  7. Article
  8. Association between serum gastric biomarkers and metabolic syndrome.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ganka Y BekyarovaDepartment of Physiology and Pathophysiology, Medical University of Varna, 9002 Varna, Bulgaria.
Deyana G VankovaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Medical University of Varna, 9002 Varna, Bulgaria.ORCID 0000-0002-6542-538X
Valentina H MadjovaDepartment of General Medicine, Medical University of Varna, 9002 Varna, Bulgaria.
Nicolai A BekyarovDepartment of General Medicine, Medical University of Varna, 9002 Varna, Bulgaria.
Ayshe S SalimDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Medical University of Varna, 9002 Varna, Bulgaria.ORCID 0000-0002-1422-7121
Diana G IvanovaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Medical University of Varna, 9002 Varna, Bulgaria.ORCID 0000-0002-4502-081X
Stefka M StoevaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Medical University of Varna, 9002 Varna, Bulgaria.
Daniela I GerovaDepartment of Clinical Laboratory, Medical University Varna, 9002 Varna, Bulgaria.
Yoana D Kiselova-KanevaDepartment of Biochemistry, Molecular Medicine and Nutrigenomics, Medical University of Varna, 9002 Varna, Bulgaria.ORCID 0000-0001-9692-6227
Medical University of Varna · BG

Funding

European Commission BG-RRP-2.004-0009-C02
6 · The paper itself

Abstract

Endothelial dysfunction is one of the major factors in the pathogenesis of metabolic syndrome (MetS), and its molecular mechanisms are not completely understood. The present study aimed to examine the connection between nuclear factor2-related factor2 (Nrf2), nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), heme oxygenase 1 (HO-1), and plasma asymmetric dimethylarginine (ADMA) and malondialdehyde (MDA) in people with MetS. Participants in the study were as follows: with MetS (

Indexed as

Metabolic SyndromeNF-kappa BArginineHeme Oxygenase-1HumansInflammationLeukocytes, MononuclearNF-E2-Related Factor 2Oxidative StressArginineHeme Oxygenase-1HMOX1 protein, humanNFE2L2 protein, humanNF-E2-Related Factor 2NF-kappa BN,N-dimethylarginineendothelial dysfunctionHO-1NF-kBNrf2oxidative stressPBMCplasma ADMA

Identifiers

PMID38069389
PMCPMC10707226
OpenAlexW4389264721

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.