Evidence map›Paper›PMID 38069341›Full record

ArticleInternational journal of molecular sciences2023

In Silico and In Vitro Approach for Evaluation of the Anti-Inflammatory and Antioxidant Potential of Mygalin.

Abraham Espinoza-Culupú, Nayara Del Santos, Mariella Farfán-López, Elizabeth Mendes, Pedro Ismael da Silva Junior, Monamaris Marques Borges

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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  6. Special Issue "Polyamines in Aging and Disease".International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Abraham Espinoza-CulupúSchool of Nursing, Universidad Cesar Vallejo (UCV), Lima 15314, Peru.ORCID 0000-0002-5553-6385
Nayara Del SantosBacteriology Laboratory, Butantan Institute, São Paulo 05585-000, Brazil.
Mariella Farfán-LópezSchool of Nursing, Universidad Cesar Vallejo (UCV), Lima 15314, Peru.
Elizabeth MendesBacteriology Laboratory, Butantan Institute, São Paulo 05585-000, Brazil.
Pedro Ismael da Silva JuniorLaboratory for Applied Toxinology (LETA), Butantan Institute, São Paulo 05585-000, Brazil.ORCID 0000-0001-6619-6489
Monamaris Marques BorgesBacteriology Laboratory, Butantan Institute, São Paulo 05585-000, Brazil.ORCID 0000-0001-8355-5498
Instituto Butantan · BRUniversidad César Vallejo · PE

Funding

Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica 092-2016FAPESP/CeTICS 2013/07467-1National Council for Scientific and Technological Development 472744/2012-7São Paulo Research Foundation 2013/11212-9, 2020/08182-4, 2023/08292-2
6 · The paper itself

Abstract

There is a great interest in describing new molecules to be used as therapeutic targets in various diseases, particularly those that play a role in inflammatory responses and infection control. Mygalin is a synthetic analogue of spermidine, and previous studies have demonstrated its bactericidal effect against

Indexed as

AntioxidantsSpermidineAnti-Inflammatory AgentsCyclooxygenase 2HumansInflammationLipopolysaccharidesMolecular Docking SimulationReactive Oxygen SpeciesTissue DistributionAnti-Inflammatory AgentsAntioxidantsCyclooxygenase 2LipopolysaccharidesN1,N8-bis(2,5-dihydroxybenzoyl)spermidineReactive Oxygen SpeciesSpermidineacylpolyamineantioxidant activityinflammationmolecular dockingmygalin

Identifiers

PMID38069341
PMCPMC10707111
OpenAlexW4389238660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.