ArticleInternational journal of molecular sciences2023
Impact of Bariatric Surgery on Subtilisin/Kexin Type 9 (PCSK9) Gene Expression and Inflammation in the Adipose Tissue of Obese Diabetic Rats.
Adrian H Heald, Helene A Fachim, Bilal Bashir, Bethanie Garside, Safwaan Adam, Zohaib Iqbal, Akheel A Syed, Rachelle Donn, Carel W Le Roux, Mahmoud Abdelaal and 2 more
Open access · goldAbstract read
In one paragraphArticle in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors at 3 institutions in 2 countries.
Adrian H HealdFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0002-9537-4050 Helene A FachimFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Bilal BashirFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0003-3733-8331 Bethanie GarsideFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0001-9461-0042 Safwaan AdamFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Zohaib IqbalFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Akheel A SyedFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Rachelle DonnFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.ORCID 0000-0001-6976-9828 Carel W Le RouxDiabetes Complications Research Centre, Conway Institute, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0001-5521-5445 Mahmoud AbdelaalDiabetes Complications Research Centre, Conway Institute, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
James WhiteDiabetes Complications Research Centre, Conway Institute, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.
Handrean SoranFaculty of Biology, Medicine and Health, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
University of Manchester · GBSalford Royal NHS Foundation Trust · GBUniversity College Dublin · IE
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Bariatric surgery improves dyslipidaemia and reduces body weight, but it remains unclear how bariatric surgery modulates gene expression in fat cells to influence the
Indexed as
Bariatric SurgeryDiabetes Mellitus, ExperimentalAdipose TissueAnimalsGene ExpressionInflammationObesityProprotein Convertase 9Proprotein ConvertasesRatsRats, Sprague-DawleyRats, ZuckerReceptors, LDLSerine EndopeptidasesSubtilisinTumor Necrosis Factor-alphaPCSK9 protein, ratProprotein Convertase 9Proprotein ConvertasesReceptors, LDLSerine EndopeptidasesSubtilisinTumor Necrosis Factor-alphabariatric surgerydiabetesfat tissueobesityPCSK9Zucker Diabetic Sprague Dawley
Identifiers
PMID38069302
PMCPMC10707086
OpenAlexW4389193180
What OpenQuestion holds
Texttitle and abstract
LicenceCC BY
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