Evidence map›Paper›PMID 38069294›Full record

ReviewInternational journal of molecular sciences2023

Pyrrolizidine Alkaloids-Pros and Cons for Pharmaceutical and Medical Applications.

Kavindi Jayawickreme, Dawid Świstak, Ewa Ozimek, Emilia Reszczyńska, Anna Rysiak, Anna Makuch-Kocka, Agnieszka Hanaka

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kavindi JayawickremeStudent Scientific Club of Phytochemists, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.
Dawid ŚwistakStudent Scientific Club of Phytochemists, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.
Ewa OzimekDepartment of Industrial and Environmental Microbiology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.ORCID 0000-0003-4609-9133
Emilia ReszczyńskaDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, Chodźki St. 1, 20-093 Lublin, Poland.
Anna RysiakDepartment of Botany, Mycology, and Ecology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.
Anna Makuch-KockaDepartment of Pharmacology, Medical University of Lublin, Radziwiłłowska St. 11, 20-080 Lublin, Poland.ORCID 0000-0001-8082-535X
Agnieszka HanakaDepartment of Plant Physiology and Biophysics, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.ORCID 0000-0002-0648-5681
Maria Curie-Skłodowska University · PLMedical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterocyclic organic compounds named pyrrolizidine alkaloids (PAs) belong to a group of alkaloids and are synthesized by either plants or microorganisms. Therefore, they are naturally occurring secondary metabolites. They are found in species applied in the pharmaceutical and food industries, thus a thorough knowledge of their pharmacological properties and toxicology to humans is of great importance for their further safe employment. This review is original because it synthesizes knowledge of plant and microbial PAs, which is unusual in the scientific literature. We have focused on the

Indexed as

Pyrrolizidine AlkaloidsHumansPharmaceutical PreparationsPlantsPharmaceutical PreparationsPyrrolizidine Alkaloidsanticancer activityantimicrobial activityBoraginaceaecytochrome P450food safetygenotoxicityhepatotoxicitymicrobial alkaloidspyrrolizidine alkaloidStreptomyces

Identifiers

PMID38069294
PMCPMC10706944
OpenAlexW4389206746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.