Evidence map›Paper›PMID 38069236›Full record

ArticleInternational journal of molecular sciences2023

Time-Resolved X-ray Observation of Intracellular Crystallized Protein in Living Animal.

Masahiro Kuramochi, Ibuki Sugawara, Yoichi Shinkai, Kazuhiro Mio, Yuji C Sasaki

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Masahiro KuramochiGraduate School of Science and Engineering, Ibaraki University, Hitachi 316-8511, Japan.ORCID 0000-0003-1643-3997
Ibuki SugawaraGraduate School of Science and Engineering, Ibaraki University, Hitachi 316-8511, Japan.
Yoichi ShinkaiMolecular Neurobiology Research Group, Biomedical Research Institute, National Institute of Advance Industrial Science and Technology (AIST), Tsukuba 305-8566, Japan.ORCID 0000-0001-8366-6278
Kazuhiro MioAIST-UTokyo Advanced Operando-Measurement Technology Open Innovation Laboratory (OPERANDO-OIL), National Institute of Advanced Industrial Science and Technology (AIST), Kashiwa 277-8565, Japan.ORCID 0000-0002-1655-8231
Yuji C SasakiGraduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8561, Japan.ORCID 0000-0003-3403-237X
Ibaraki University · JPNational Institute of Advanced Industrial Science and Technology · JPThe University of Tokyo · JP

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Understanding the cellular environment as molecular crowding that supports the structure-specific functional expression of biomolecules has recently attracted much attention. Time-resolved X-ray observations have the remarkable capability to capture the structural dynamics of biomolecules with subnanometre precision. Nevertheless, the measurement of the intracellular dynamics within live organisms remains a challenge. Here, we explore the potential of utilizing crystallized proteins that spontaneously form intracellular crystals to investigate their intracellular dynamics via time-resolved X-ray observations. We generated transgenic

Indexed as

Caenorhabditis elegansProteinsAnimalsCrystallography, X-RayRadiographyX-Ray DiffractionX-RaysProteinsCaenorhabditis eleganscrystallized proteindiffracted X-ray blinkingfluorescent recovery after photobleachingin vivo

Identifiers

PMID38069236
PMCPMC10706802
OpenAlexW4389145010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.