Evidence map›Paper›PMID 38069189›Full record

ArticleInternational journal of molecular sciences2023

Decelerated Epigenetic Aging in Long Livers.

Zulfiya G Guvatova, Anastasiya A Kobelyatskaya, Elena A Pudova, Irina V Tarasova, Anna V Kudryavtseva, Olga N Tkacheva, Irina D Strazhesko, Alexey A Moskalev

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Quantification of Epigenetic Aging in Public Health.Annual review of public health · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zulfiya G GuvatovaRussian Clinical Research Center for Gerontology, Pirogov Russian National Research Medical University, Ministry of Healthcare of the Russian Federation, Moscow 129226, Russia.ORCID 0000-0003-3494-9807
Anastasiya A KobelyatskayaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia.
Elena A PudovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia.ORCID 0000-0002-5492-1361
Irina V TarasovaRussian Clinical Research Center for Gerontology, Pirogov Russian National Research Medical University, Ministry of Healthcare of the Russian Federation, Moscow 129226, Russia.
Anna V KudryavtsevaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia.ORCID 0000-0002-3722-8207
Olga N TkachevaRussian Clinical Research Center for Gerontology, Pirogov Russian National Research Medical University, Ministry of Healthcare of the Russian Federation, Moscow 129226, Russia.
Irina D StrazheskoRussian Clinical Research Center for Gerontology, Pirogov Russian National Research Medical University, Ministry of Healthcare of the Russian Federation, Moscow 129226, Russia.
Alexey A MoskalevRussian Clinical Research Center for Gerontology, Pirogov Russian National Research Medical University, Ministry of Healthcare of the Russian Federation, Moscow 129226, Russia.ORCID 0000-0002-3248-1633
Engelhardt Institute of Molecular Biology · RUPirogov Russian National Research Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetic aging is a hot topic in the field of aging research. The present study estimated epigenetic age in long-lived individuals, who are currently actively being studied worldwide as an example of successful aging due to their longevity. We used Bekaert's blood-based age prediction model to estimate the epigenetic age of 50 conditionally "healthy" and 45 frail long-livers over 90 years old. Frailty assessment in long-livers was conducted using the Frailty Index. The control group was composed of 32 healthy individuals aged 20-60 years. The DNA methylation status of 4 CpG sites (

Indexed as

Epigenesis, GeneticFrailtyAged, 80 and overAgingCpG IslandsDNA MethylationFemaleHumansLongevityMaleagingDNA methylationepigenetic clocklong liverspyrosequencing

Identifiers

PMID38069189
PMCPMC10707056
OpenAlexW4389098542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.