Evidence map›Paper›PMID 38069171›Full record

ArticleInternational journal of molecular sciences2023

Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells.

Akos Janos Varga, Istvan Balazs Nemeth, Lajos Kemeny, Janos Varga, Laszlo Tiszlavicz, Dinesh Kumar, Steven Dodd, Alec W M Simpson, Tunde Buknicz, Rob Beynon and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. The prognostic value and molecular mechanisms ofTranslational cancer research · 2026
    Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Akos Janos VargaDepartment of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 7BE, UK.
Istvan Balazs NemethDepartment of Dermatology and Allergology, University of Szeged, 6720 Szeged, Hungary.
Lajos KemenyDepartment of Dermatology and Allergology, University of Szeged, 6720 Szeged, Hungary.ORCID 0000-0002-2119-9501
Janos VargaDepartment of Dermatology and Allergology, University of Szeged, 6720 Szeged, Hungary.
Laszlo TiszlaviczDepartment of Pathology, University of Szeged, 6725 Szeged, Hungary.
Dinesh KumarDepartment of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 7BE, UK.
Steven DoddDepartment of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 7BE, UK.
Alec W M SimpsonDepartment of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 7BE, UK.
Tunde BukniczDepartment of Dermatology and Allergology, University of Szeged, 6720 Szeged, Hungary.
Rob BeynonDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.
Deborah SimpsonDepartment of Biochemistry, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7BE, UK.
Tibor KrenacsDepartment of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0001-9164-065X
Graham J DockrayDepartment of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 7BE, UK.
Andrea VarroDepartment of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 7BE, UK.
University of Liverpool · GBUniversity of Szeged · HUSemmelweis University · HU

Funding

Hungarian Scientific Research Fund OTKA125509
6 · The paper itself

Abstract

Micro-environmental factors, including stromal and immune cells, cytokines, and circulating hormones are well recognized to determine cancer progression. Melanoma cell growth was recently shown to be suppressed by cholecystokinin/gastrin (CCK) receptor antagonists, and our preliminary data suggested that melanoma patients with

Indexed as

MelanomaSkin NeoplasmsGastrinsHumansProteomicsReceptor, Cholecystokinin BReceptors, Cholecystokiningastrin IGastrinsReceptor, Cholecystokinin BReceptors, CholecystokininCCK2RCCKBRgastrininvasionmelanomamigrationMMP-2secretomeTIMP-3

Identifiers

PMID38069171
PMCPMC10706711
OpenAlexW4389087044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.