Evidence map›Paper›PMID 38069100›Full record

ArticleInternational journal of molecular sciences2023

Early Castration in Horses Does Not Impact Osteoarticular Metabolism.

Marion Rouge, Florence Legendre, Razan Elkhatib, Christelle Delalande, Juliette Cognié, Fabrice Reigner, Philippe Barrière, Stefan Deleuze, Vincent Hanoux, Philippe Galéra and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Marion RougeUniversité de Caen-Normandie, OeReCa, 14000 Caen, France.
Florence LegendreUniversité de Caen Normandie BIOTARGEN, 14000 Caen, France.ORCID 0000-0002-9951-1585
Razan ElkhatibUniversité de Caen-Normandie, OeReCa, 14000 Caen, France.
Christelle DelalandeUniversité de Caen-Normandie, OeReCa, 14000 Caen, France.
Juliette CogniéINRAE, Université de Tours, Centre de Recherche de Tours, UMR PRC, 37380 Nouzilly, France.
Fabrice ReignerINRAE, Université de Tours, Centre de Recherche de Tours, UEPAO, 37380 Nouzilly, France.
Philippe BarrièreINRAE, Université de Tours, Centre de Recherche de Tours, UEPAO, 37380 Nouzilly, France.
Stefan DeleuzeUniversité de Liège, 4000 Liège, Belgium.ORCID 0000-0003-3076-5779
Vincent HanouxUniversité de Caen-Normandie, OeReCa, 14000 Caen, France.
Philippe GaléraUniversité de Caen Normandie BIOTARGEN, 14000 Caen, France.ORCID 0000-0002-7797-2284
Hélène Bouraïma-LelongUniversité de Caen-Normandie, OeReCa, 14000 Caen, France.
Université de Caen Normandie · FRUniversité de Tours · FRBiologie, Génétique et Thérapies ostéoArticulaires et RespiratoiresUniversity of Liège · BE

Funding

Fonds Eperon EQUISTEM, N80-2014,917CB194GIS CENTAURE equine research EQUISTEM-G,014CJ061Institut Français du Cheval et de l'ÉquitationMinistère de l'Enseignement Supérieur, de la Recherche et de l'InnovationRégion Normandie
6 · The paper itself

Abstract

The castration of stallions is traditionally performed after puberty, at around the age of 2 years old. No studies have focused on the effects of early castration on osteoarticular metabolism. Thus, we aimed to compare early castration (3 days after birth) with traditional castration (18 months of age) in horses. Testosterone and estradiol levels were monitored from birth to 33 months in both groups. We quantified the levels of biomarkers of cartilage and bone anabolism (CPII and N-MID) and catabolism (CTX-I and CTX-II), as well as of osteoarthritis (HA and COMP) and inflammation (IL-6 and PGE

Indexed as

OsteoarthritisSexual MaturationAnimalsBiomarkersCastrationEstradiolHorsesInflammationMaleOrchiectomyTestosteroneBiomarkersEstradiolTestosteronebonecartilagecastrationhorsein vivo metabolismsteroid hormones

Identifiers

PMID38069100
PMCPMC10706761
OpenAlexW4389051403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.