Evidence map›Paper›PMID 38069092›Full record

ArticleInternational journal of molecular sciences2023

Unveiling the Potent Fibrino(geno)lytic, Anticoagulant, and Antithrombotic Effects of Papain, a Cysteine Protease from

Hye Ryeon Yang, Most Nusrat Zahan, Yewon Yoon, Kyuri Kim, Du Hyeon Hwang, Woo Hyun Kim, Il Rae Rho, Euikyung Kim, Changkeun Kang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Various parts ofFrontiers in molecular biosciences · 2026
    Review
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  3. Synergistic Effects of Carrot (Food science & nutrition · 2025
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Hye Ryeon YangDepartment of Basic Veterinary Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Most Nusrat ZahanDepartment of Basic Veterinary Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Yewon YoonDepartment of Basic Veterinary Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Kyuri KimDepartment of Basic Veterinary Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.
Du Hyeon HwangDepartment of Basic Veterinary Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0002-7228-3340
Woo Hyun KimDepartment of Basic Veterinary Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0002-6874-6787
Il Rae RhoInstitutes of Agriculture and Life Science, Gyeongsang National University, Jinju 52828, Republic of Korea.
Euikyung KimDepartment of Basic Veterinary Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0003-3356-3072
Changkeun KangDepartment of Basic Veterinary Medicine, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0002-5114-5096
Gyeongsang National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While fibrinolytic enzymes and thrombolytic agents offer assistance in treating cardiovascular diseases, the existing options are associated with a range of adverse effects. In our previous research, we successfully identified ficin, a naturally occurring cysteine protease that possesses unique fibrin and fibrinogenolytic enzymes, making it suitable for both preventing and treating cardiovascular disorders linked to thrombosis. Papain is a prominent cysteine protease derived from the latex of

Indexed as

CaricaCysteine ProteasesHemostaticsThrombosisAnimalsAnticoagulantsCarrageenanFibrinFibrinogenFibrinolytic AgentsLatexPapainRatsRats, Sprague-DawleyAnticoagulantsCarrageenanCysteine ProteasesFibrinFibrinogenFibrinolytic AgentsHemostaticsLatexPapainblood coagulationcysteine proteasepapainthrombosisκ-carrageenan

Identifiers

PMID38069092
PMCPMC10706441
OpenAlexW4389051683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.