ReviewInternational journal of molecular sciences2023
Polyarteritis Nodosa: Old Disease, New Etiologies.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach From the Writing Committee of the American Society for Apheresis: The Tenth Special Issue.Journal of clinical apheresis · 2026Guideline
- Clinical manifestations, prognostic impact, and relapse in polyarteritis nodosa: a systematic review and meta-analysis.Rheumatology international · 2026Pooled it
- Autoimmune diseases involving the gastrointestinal tract: clinical patterns, imaging spectrum, and complications.Abdominal radiology (New York) · 2026Review
- Paraneoplastic necrotizing medium-vessel vasculitis mimicking polyarteritis nodosa with large-vessel involvement.Clinical rheumatology · 2026Article
- Temporal artery biopsy in polyarteritis nodosa: a case-based narrative literature review.Clinical rheumatology · 2026Review
- Multi-generational koala pedigree analysis reveals rapid changes in heritable provirus load associated with life history traits.Nature communications · 2026Article
- Neuroimmune Interactions in Stress and Depression: Exploring the Molecular and Cellular Mechanisms within the Neuroinflammation-depression Nexus.Current medicinal chemistry · 2026Review
- Atypical Vasculitis Phenotype with Concomitant Medium- and Small-Vessel Involvement: A Case Report Highlighting Diagnostic and Pathological Challenges.International journal of nephrology and renovascular disease · 2026Article
- Fever of unknown origin, muscle weakness, and an adrenal nodule-the cat we chased like a hare: a case report.Journal of medical case reports · 2025Article
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- Lymphoproliferative Disorders Mimicking Rheumatologic Disease: A Clinical Reasoning Perspective.Current allergy and asthma reports · 2025Review
- Cutaneous Arteritis Complicated by Crohn's Disease.Internal medicine (Tokyo, Japan) · 2025Article
- Vasculitis associated with VEXAS syndrome.Rheumatology (Oxford, England) · 2025Article
- Spontaneous accessory renal artery aneurysm rupture as a first presentation of polyarteritis nodosa: a case report and review of literature.Annals of medicine and surgery (2012) · 2025Article
- Critical Limb Threatening Ischemia Due to Severe Polyarteritis Nodosa.Internal medicine (Tokyo, Japan) · 2025Article
- Complex presentation of polyarteritis nodosa: Renal pseudoaneurysm rupture and bowel ischemia: A case report.International journal of surgery case reports · 2025Article
- Polyarteritis nodosa initially presenting as ocular motility impairment and diplopia with subsequent development of bilateral central retinal artery occlusion: A case report.American journal of ophthalmology case reports · 2025Article
- Predominantly multiple focal non-cystic renal lesions: an imaging approach.Abdominal radiology (New York) · 2025Review
- Case Report: A case of cutaneous polyarteritis nodosa in a child following a streptococcal infection.Frontiers in pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyarteritis nodosa (PAN), also known as panarteritis nodosa, represents a form of necrotizing vasculitis that predominantly affects medium-sized vessels, although it is not restricted to them and can also involve smaller vessels. The clinical presentation is heterogeneous and characterized by a significant number of patients exhibiting general symptoms, including asthenia, fever, and unintended weight loss. Although PAN can involve virtually any organ, it preferentially affects the skin, nervous system, and the gastrointestinal tract. Orchitis is a rare but specific manifestation of PAN. The absence of granulomas, glomerulonephritis, and anti-neutrophil cytoplasmic antibodies serves to distinguish PAN from other types of vasculitis. Major complications consist of hemorrhagic and thrombotic events occurring in mesenteric, cardiac, cerebral, and renal systems. Historically, PAN was frequently linked to hepatitis B virus (HBV) infection, but this association has dramatically changed in recent years due to declining HBV prevalence. Current epidemiological research often identifies a connection between PAN and genetic syndromes as well as neoplasia. This article provides a comprehensive review of PAN, specifically focusing on the progression of its clinical manifestations over time.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.