Evidence map›Paper›PMID 38068980›Full record

ArticleInternational journal of molecular sciences2023

Transcriptomics of MASLD Pathobiology in African American Patients in the Washington DC Area

Tanmoy Mondal, Coleman I Smith, Christopher A Loffredo, Ruth Quartey, Gemeyel Moses, Charles D Howell, Brent Korba, Bernard Kwabi-Addo, Gail Nunlee-Bland, Leanna R Rucker and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Tanmoy MondalDepartment of Biology, Howard University, Washington, DC 20059, USA.ORCID 0000-0001-6542-5163
Coleman I SmithMedStar-Georgetown Transplantation Institute, Georgetown University School of Medicine, Washington, DC 20007, USA.
Christopher A LoffredoDepartment of Oncology, Georgetown University, Washington, DC 20007, USA.
Ruth QuarteyDepartment of Internal Medicine, College of Medicine, Howard University, Washington, DC 20007, USA.
Gemeyel MosesDepartment of Biology, Howard University, Washington, DC 20059, USA.
Charles D HowellDepartment of Internal Medicine, College of Medicine, Howard University, Washington, DC 20007, USA.
Brent KorbaDepartment of Microbiology & Immunology, Georgetown University, Washington, DC 20007, USA.
Bernard Kwabi-AddoDepartment of Biochemistry, College of Medicine, Howard University, Washington, DC 20059, USA.
Gail Nunlee-BlandDepartments of Pediatrics and Child Health, College of Medicine, Howard University, Washington, DC 20059, USA.
Leanna R RuckerDepartment of Internal Medicine, MedStar Georgetown University Hospital, Washington, DC 20007, USA.
Jheannelle JohnsonDepartment of Biology, Howard University, Washington, DC 20059, USA.
Somiranjan GhoshDepartment of Biology, Howard University, Washington, DC 20059, USA.ORCID 0000-0002-5280-7418
Howard University · USGeorgetown University · US

Funding

Georgetown-Howard Universities Center for Clinical and Translational Science (GHUUL1TR000101 · NCATS · GEORGETOWN UNIVERSITY · PI MELLMAN, THOMAS A, VERBALIS, JOSEPH G · 2012 to 2015
$19.3M
Georgetown-Howard Universities Center for Clinical and Translational Science (GHUUL1RR031975 · NCRR · GEORGETOWN UNIVERSITY · PI VERBALIS, JOSEPH G · 2010 to 2011
$14.6M
Fatty Liver Disease in African AmericansP20CA242617 · NCI · HOWARD UNIVERSITY · PI ADAMS-CAMPBELL, LUCILE LAUREN, TAYLOR, TELETIA RENEE · 2019 to 2022
$1.2M
Fatty Liver Disease in African AmericansP20CA242611 · NCI · GEORGETOWN UNIVERSITY · PI ADAMS-CAMPBELL, LUCILE LAUREN, TAYLOR, TELETIA RENEE · 2019 to 2022
$868k
NCATS NIH HHS UL1 TR000101NCATS NIH HHS UL1TR000101NCI NIH HHS CA262617-01NCI NIH HHS P20 CA242611NCI NIH HHS P20 CA242617NCRR NIH HHS UL1 RR031975
6 · The paper itself

Abstract

Metabolic-dysfunction-associated steatotic liver disease (MASLD) is becoming the most common chronic liver disease worldwide and is of concern among African Americans (AA) in the United States. This pilot study evaluated the differential gene expressions and identified the signature genes in the disease pathways of AA individuals with MASLD. Blood samples were obtained from MASLD patients (

Indexed as

Fatty LiverLiver NeoplasmsMetabolic DiseasesBlack or African AmericanGene Expression ProfilingHumansPilot ProjectsAfrican AmericansMASLDNAFLDpathophysiologytranscriptomic analysis

Identifiers

PMID38068980
PMCPMC10706626
OpenAlexW4388945414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.