Evidence map›Paper›PMID 38068960›Full record

ArticleInternational journal of molecular sciences2023

Novel

Chenelle A Caron-Godon, Stefania Della Vecchia, Alessandro Romano, Stefano Doccini, Flavio Dal Canto, Rosa Pasquariello, Anna Rubegni, Roberta Battini, Filippo Maria Santorelli, D Moira Glerum and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Disease models of Leigh syndrome: From yeast to organoids.Journal of inherited metabolic disease · 2024
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Chenelle A Caron-GodonDepartment of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada.ORCID 0009-0004-1115-1709
Stefania Della VecchiaDepartment of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, Viale Pieraccini, 6, 50139 Florence, Italy.
Alessandro RomanoExperimental Neuropathology Unit, Division of Neuroscience, Institute of Experimental Neurology, IRCCS Ospedale San Raffaele Scientific Institute, 20132 Milan, Italy.ORCID 0000-0003-2766-8847
Stefano DocciniMolecular Medicine for Neurodegenerative and Neuromuscular Disease Unit, IRCCS Stella Maris Foundation, 56128 Pisa, Italy.ORCID 0000-0002-5534-8253
Flavio Dal CantoMolecular Medicine for Neurodegenerative and Neuromuscular Disease Unit, IRCCS Stella Maris Foundation, 56128 Pisa, Italy.ORCID 0000-0002-6447-4585
Rosa PasquarielloNeuroradiology, IRCCS Stella Maris Foundation, 56128 Pisa, Italy.
Anna RubegniMolecular Medicine for Neurodegenerative and Neuromuscular Disease Unit, IRCCS Stella Maris Foundation, 56128 Pisa, Italy.
Roberta BattiniDevelopmental Neurology and Neurorehabilitation Unit, IRCCS Stella Maris Foundation, 56128 Pisa, Italy.ORCID 0000-0002-7889-1355
Filippo Maria SantorelliMolecular Medicine for Neurodegenerative and Neuromuscular Disease Unit, IRCCS Stella Maris Foundation, 56128 Pisa, Italy.ORCID 0000-0002-1359-9062
D Moira GlerumDepartment of Biology, University of Waterloo, Waterloo, ON N2L 3G1, Canada.ORCID 0000-0002-2307-0568
Claudia NestiMolecular Medicine for Neurodegenerative and Neuromuscular Disease Unit, IRCCS Stella Maris Foundation, 56128 Pisa, Italy.ORCID 0000-0001-5769-8655
Fondazione Stella Maris · ITUniversity of Waterloo · CANeuroscience Institute · ITUniversity of Pisa · IT

Funding

Natural Sciences and Engineering Research Council RGPIN 227415
6 · The paper itself

Abstract

Genetic defects in the nuclear encoded subunits and assembly factors of cytochrome c oxidase (mitochondrial complex IV) are very rare and are associated with a wide variety of phenotypes. Biallelic pathogenic variants in the COX11 protein were previously identified in two unrelated children with infantile-onset mitochondrial encephalopathies. Through comprehensive clinical, genetic and functional analyses, here we report on a new patient harboring novel heterozygous variants in

Indexed as

Mitochondrial DiseasesSaccharomyces cerevisiae ProteinsAmino Acid SequenceChildCopper Transport ProteinsElectron Transport Chain Complex ProteinsElectron Transport Complex IVFibroblastsHumansMembrane ProteinsMitochondrial ProteinsMutationSaccharomyces cerevisiaeCopper Transport ProteinsCOX11 protein, humanCOX11 protein, S cerevisiaeElectron Transport Chain Complex ProteinsElectron Transport Complex IVMembrane ProteinsMitochondrial ProteinsSaccharomyces cerevisiae ProteinsCOX11 mutationCOX11 protein structuremitochondrial diseasesyeast model

Identifiers

PMID38068960
PMCPMC10706101
OpenAlexW4388932000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.