Evidence map›Paper›PMID 38068887›Full record

ArticleInternational journal of molecular sciences2023

The Antidepressant Activity of a Taurine-Containing Derivative of 4-Phenylpyrrolidone-2 in a Model of Chronic Unpredictable Mild Stress.

Denis A Borozdenko, Darya I Gonchar, Vlada I Bogorodova, Dmitri V Tarasenko, Evgeniya P Kramarova, Svetlana S Khovanova, Yaroslav V Golubev, Nina M Kiseleva, Tatiana A Shmigol, Aiarpi A Ezdoglian and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Denis A BorozdenkoInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.ORCID 0000-0002-6797-9722
Darya I GoncharInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.ORCID 0000-0003-3327-692X
Vlada I BogorodovaInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.
Dmitri V TarasenkoInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.
Evgeniya P KramarovaInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.
Svetlana S KhovanovaInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.
Yaroslav V GolubevInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.ORCID 0000-0003-3816-4169
Nina M KiselevaInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.ORCID 0000-0003-1754-9051
Tatiana A ShmigolInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.ORCID 0000-0002-5195-0845
Aiarpi A EzdoglianInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.
Konstantin A SobyaninInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.ORCID 0000-0001-7335-5468
Vadim V NegrebetskyInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.ORCID 0000-0001-6852-8942
Yuri I BaukovInstitute of Pharmacy and Medicinal Chemistry, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.
Pirogov Russian National Research Medical University · RU

Funding

Russian Science Foundation 21-73-20250
6 · The paper itself

Abstract

This study investigates the therapeutic potential of a new compound, potassium 2-[2-(2-oxo-4-phenylpyrrolidin-1-yl) acetamido]ethanesulfonate (Compound

Indexed as

Antidepressive AgentsFluoxetineAnimalsBehavior, AnimalCorticosteroneDepressionDisease Models, AnimalMalePyrrolidinonesRatsRats, WistarStress, Psychological4-phenylpyrrolidone-2Antidepressive AgentsCorticosteroneFluoxetinePyrrolidinones4-phenylpyrrolidinone-2 derivativeantidepressant activitychronic unpredictable mild stressfluoxetinehormones

Identifiers

PMID38068887
PMCPMC10705968
OpenAlexW4388866189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.