Evidence map›Paper›PMID 38068880›Full record

ArticleInternational journal of molecular sciences2023

Anti-Proliferative Potential of Cynaroside and Orientin-In Silico (DYRK2) and In Vitro (U87 and Caco-2) Studies.

Lucia Camelia Pirvu, Lucia Pintilie, Adrian Albulescu, Amalia Stefaniu, Georgeta Neagu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
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  5. Review
  6. Article
  7. Linking Variability in Phytochemical Composition with Safety Profile ofInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lucia Camelia PirvuDepartment of Pharmaceutical Biotechnologies, National Institute of Chemical Pharmaceutical R&D-ICCF Bucharest, 112 Vitan, 031299 Bucharest, Romania.ORCID 0000-0002-5032-5079
Lucia PintilieDepartment of Synthesis of Bioactive Substances and Pharmaceutical Technologies, National Institute of Chemical Pharmaceutical R&D-ICCF Bucharest, 112 Vitan, 031299 Bucharest, Romania.ORCID 0000-0002-1036-7653
Adrian AlbulescuDepartment of Pharmacology, National Institute of Chemical Pharmaceutical R&D-ICCF Bucharest, 112 Vitan, 031299 Bucharest, Romania.
Amalia StefaniuDepartment of Pharmaceutical Biotechnologies, National Institute of Chemical Pharmaceutical R&D-ICCF Bucharest, 112 Vitan, 031299 Bucharest, Romania.ORCID 0000-0002-7254-7991
Georgeta NeaguDepartment of Pharmacology, National Institute of Chemical Pharmaceutical R&D-ICCF Bucharest, 112 Vitan, 031299 Bucharest, Romania.ORCID 0000-0003-3087-3892
National Institute For Chemical Pharmaceutical Research and Development · RO

Funding

National Plan for Research and Development and Innovation 2022-2027 PN 23-28 04 01"Nucleu" Program 1N/2023, PN 23-28
6 · The paper itself

Abstract

Luteolin derivates are plant compounds with multiple benefits for human health. Stability to heat and acid hydrolysis and high resistance to (auto)oxidation are other arguments for the laden interest in luteolin derivates today. The present study was designed to compare the in silico and in vitro anti-proliferative potential of two luteolin derivates, luteolin-7-

Indexed as

Antineoplastic AgentsCarcinomaCurcuminGlioblastomaCaco-2 CellsFlavonoidsGlucosidesHumansLigandsLuteolinAntineoplastic AgentsCurcuminFlavonoidsGlucosidesLigandsLuteolinluteolin-7-glucosideorientindual specificity tyrosine phosphorylation-regulated kinase 2human colon carcinoma Caco-2human glioblastoma U87in vitro studiesluteolin-7-O-glucosideluteolin-8-C-glucosidemolecular docking

Identifiers

PMID38068880
PMCPMC10705913
OpenAlexW4388866417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.