Evidence map›Paper›PMID 38068820›Full record

Trial reportNutrients2023

Reversal of Conditioned Food Aversion Using a Cognitive Intervention: A Sham-Controlled, Randomized, Parallel Study.

Adoracion Nieto, Dan M Livovsky, Fernando Azpiroz

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05897411 (Factors That Determine the Responses to Meal Ingestion), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05897411 nacompletednot on this map

Factors That Determine the Responses to Meal Ingestion: Deconditioning of Acquired Food Aversion

TypeinterventionalSponsorHospital Universitari Vall d'Hebron Research InstituteRan2023 to 2023Enrolled12ConditionsHealthyArmsUnmasking previous conditioning procedure, No unmasking of previous conditioning
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adoracion NietoDigestive System Research Unit, University Hospital Vall d'Hebron, 08035 Barcelona, Spain.
Dan M LivovskyDigestive System Research Unit, University Hospital Vall d'Hebron, 08035 Barcelona, Spain.ORCID 0000-0002-8212-9638
Fernando AzpirozDigestive System Research Unit, University Hospital Vall d'Hebron, 08035 Barcelona, Spain.ORCID 0000-0002-7327-960X

Funding

Ministerio de Ciencia e Innovación PID2021-122295OB-I00
6 · The paper itself

Abstract

backgroundAversive conditioning weakens the gratifying value of a comfort meal. The aim was to determine the effect of a cognitive intervention to reverse aversive conditioning and restore hedonic postprandial response.

methodsThis was a randomized, sham-controlled, single-blind, parallel study that was conducted on 12 healthy women (

resultsAt initial exposure, the comfort meal produced a rewarding experience that was impaired using aversive conditioning; upon re-exposure to the original meal, the cognitive intervention increased meal wanting and liking; improved digestive wellbeing and mood; tended to reduce postprandial satiety, bloating/fullness; and abolished discomfort/pain, thereby restoring the hedonic value of the comfort meal. By contrast, sham intervention had no effects, and the postprandial sensations remained like the responses to the offending meal.

conclusionIn this proof-of-concept study, we demonstrate that in healthy women, a mild, short-term acquired aversion to a comfort meal can be reversed using a cognitive intervention. CLINICALTRIALS: gov ID: NCT05897411.

Indexed as

EatingSatiationCognitionEmotionsFemaleHumansPostprandial PeriodSingle-Blind Methodaversive conditioningcognitive interventiondigestive sensationsdigestive wellbeingeating behaviourfood valencePavlovian conditioningpostprandial symptoms

Identifiers

PMID38068820
PMCPMC10708304

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.