Evidence map›Paper›PMID 38068805›Full record

ArticleNutrients2023

Protein Supplementation May Dampen Positive Effects of Exercise on Glucose Homeostasis: A Pilot Weight Loss Intervention.

John A Batsis, Dakota J Batchek, Curtis L Petersen, Danae C Gross, David H Lynch, Hillary B Spangler, Summer B Cook

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Sarcopenic obesity and weight loss-induced muscle mass loss.Current opinion in clinical nutrition and metabolic care · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

John A BatsisDivision of Geriatric Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA.ORCID 0000-0002-0845-4416
Dakota J BatchekDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Curtis L PetersenThe Dartmouth Institute for Health Policy, Dartmouth College, Hanover, NH 03755, USA.
Danae C GrossDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0003-3892-9408
David H LynchDivision of Geriatric Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA.ORCID 0000-0002-2512-9367
Hillary B SpanglerDivision of Geriatric Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA.
Summer B CookDepartment of Kinesiology, University of New Hampshire, Durham, NH 03824, USA.
University of North Carolina at Chapel Hill · USDartmouth College · USUniversity of New Hampshire · US

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
SYNERGY: The Dartmouth Center for clinical and Translational ScienceUL1TR001086 · NCATS · DARTMOUTH COLLEGE · PI GREEN, ALAN I · 2013 to 2017
$18.3M
Mobile Health Obesity Wellness Intervention in Rural Older Adults_Res1K23AG051681 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BATSIS, JOHN A. · 2016 to 2022
$1.1M
ACL HHS U48DP005018CDC HHS UL1TR001086NCATS NIH HHS UL1 TR001086NCATS NIH HHS UL1 TR002489NCATS NIH HHS UM1 TR004406NCCDPHP CDC HHS U48 DP005018NIA NIH HHS K23 AG051681NIA NIH HHS K23AG051681
6 · The paper itself

Abstract

backgroundThe role of protein in glucose homeostasis has demonstrated conflicting results. However, little research exists on its impact following weight loss. This study examined the impact of protein supplementation on glucose homeostasis in older adults >65 years with obesity seeking to lose weight.

methodsA 12-week, nonrandomized, parallel group intervention of protein (PG) and nonprotein (NPG) arms for 28 older rural adults (body mass index (BMI) ≥ 30 kg/m

resultsMean age and baseline BMI were 72.9 ± 4.4 years and 37.6 ± 6.9 kg/m

conclusionsProtein supplementation during weight loss demonstrated a smaller decrease in insulin resistance compared to the NPG, suggesting protein may potentially mitigate beneficial effects of exercise on glucose homeostasis.

Indexed as

Insulin ResistanceAgedBlood GlucoseBody Mass IndexDietary SupplementsGlucoseHomeostasisHumansInsulinWeight LossBlood GlucoseGlucoseInsulinexerciseglucose homeostasisglucose metabolisminflammationinsulin resistanceolder adultsprotein supplementationresistance trainingweight loss

Identifiers

PMID38068805
PMCPMC10707998
OpenAlexW4389144145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.