Evidence map›Paper›PMID 38068802›Full record

ArticleNutrients2023

Analysis of Gut Characteristics and Microbiota Changes with Maternal Supplementation in a Neural Tube Defect Mouse Model.

Juan Antonio Cordero-Varela, Marta Reyes-Corral, Miguel Lao-Pérez, Beatriz Fernández-Santos, Fernando Montenegro-Elvira, Lluis Sempere, Patricia Ybot-González

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Juan Antonio Cordero-VarelaInstitute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/CSIC/University of Seville, 41013 Seville, Spain.ORCID 0000-0002-7373-5433
Marta Reyes-CorralInstitute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/CSIC/University of Seville, 41013 Seville, Spain.ORCID 0000-0002-5490-0624
Miguel Lao-PérezInstitute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/CSIC/University of Seville, 41013 Seville, Spain.ORCID 0000-0001-6707-6825
Beatriz Fernández-SantosInstitute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/CSIC/University of Seville, 41013 Seville, Spain.
Fernando Montenegro-ElviraInstitute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/CSIC/University of Seville, 41013 Seville, Spain.ORCID 0000-0001-5611-5120
Lluis SempereInstitute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/CSIC/University of Seville, 41013 Seville, Spain.
Patricia Ybot-GonzálezInstitute of Biomedicine of Seville (IBiS)/Virgen del Rocío University Hospital/CSIC/University of Seville, 41013 Seville, Spain.ORCID 0000-0001-7836-2659
Instituto de Biomedicina de Sevilla · ESConsejo Superior de Investigaciones Científicas · ES

Funding

Consejería de Salud y Bienestar Social; Junta de Andalucía C-0025-2018Consejería de Salud y Bienestar Social; Junta de Andalucía EF- 0084-2016Consejería de Salud y Bienestar Social; Junta de Andalucía RH-0033-2020Consejería de Transformación Económica, Industria, Conocimiento y Universidades; Junta de Andalucía DOC_01701Consejería de Transformación Económica, Industria, Conocimiento y Universidades; Junta de Andalucía P20_01267Consejo Superior de Investigaciones Científicas; Ministerio de Ciencia e Innovación 050561Consejo Superior de Investigaciones Científicas; Ministerio de Ciencia e Innovación 202220/095Instituto de Salud Carlos III (ISCIII) and co-funded by the European Union PI17/00693Instituto de Salud Carlos III (ISCIII) and co-funded by the European Union PI20/00769
6 · The paper itself

Abstract

Adequate nutrient supply is crucial for the proper development of the embryo. Although nutrient supply is determined by maternal diet, the gut microbiota also influences nutrient availability. While currently there is no cure for neural tube defects (NTDs), their prevention is largely amenable to maternal folic acid and inositol supplementation. The gut microbiota also contributes to the production of these nutrients, which are absorbed by the host, but its role in this context remains largely unexplored. In this study, we performed a functional and morphological analysis of the intestinal tract of

Indexed as

MicrobiotaNeural Tube DefectsAnimalsDietary SupplementsDisease Models, AnimalFemaleFolic AcidInositolMicePregnancyRNA, Ribosomal, 16SFolic AcidInositolRNA, Ribosomal, 16Sfolic acidinositolloop-tailmetagenomicsmicrobiotaneural tube defectspregnancypreventionWnt/PCP

Identifiers

PMID38068802
PMCPMC10708240
OpenAlexW4389080239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.