Evidence map›Paper›PMID 38068731›Full record

ArticleNutrients2023

Oxidative Status of Ultra-Processed Foods in the Western Diet.

Lisaura Maldonado-Pereira, Carlo Barnaba, Ilce Gabriela Medina-Meza

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lisaura Maldonado-PereiraDepartment of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0001-5901-0156
Carlo BarnabaDepartment of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS 66047, USA.
Ilce Gabriela Medina-MezaDepartment of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0001-7712-4018

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultra-processed foods (UPFs) have gained substantial attention in the scientific community due to their surging consumption and potential health repercussions. In addition to their well-established poor nutritional profile, UPFs have been implicated in containing various dietary oxidized sterols (DOxSs). These DOxSs are associated with a spectrum of chronic diseases, including cardiometabolic conditions, cancer, diabetes, Parkinson's, and Alzheimer's disease. In this study, we present a comprehensive database documenting the presence of DOxSs and other dietary metabolites in >60 UPFs commonly consumed as part of the Western diet. Significant differences were found in DOxS and phytosterol content between ready-to-eat (RTE) and fast foods (FFs). Biomarker analysis revealed that DOxS accumulation, particularly 25-OH and triol, can potentially discriminate between RTEs and FFs. This work underscores the potential utility of dietary biomarkers in early disease detection and prevention. However, an essential next step is conducting exposure assessments to better comprehend the levels of DOxS exposure and their association with chronic diseases.

Indexed as

Energy IntakeFood, ProcessedChronic DiseaseDietDiet, WesternFast FoodsFood HandlingHumansOxidative StressSterolsSterolscholesterol oxidation productsdietary oxysterolslipid oxidationphytosterolsultra-processed foods

Identifiers

PMID38068731
PMCPMC10708126

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.