Evidence map›Paper›PMID 38068714›Full record

ArticleNutrients2023

Effects of Saffron Extract (Affron

Chae-Young Kim, Kayoung Ko, Seo-Hee Choi, Miri Jo, Jinhye Kim, Sunmi Yoon, Isaac Jinwon Yi, María Inés Morán-Valero, Min-Young Kwon, Johann Sohn and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Frontiers in molecular neuroscience · 2026
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Chae-Young KimBK21 Four Program, Department of Medical Science, Soonchunhyang University, Asan 31538, Republic of Korea.
Kayoung KoDepartment of Biomedical Laboratory Science, College of Medical Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.
Seo-Hee ChoiDepartment of Biomedical Laboratory Science, College of Medical Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.
Miri JoDepartment of Biomedical Laboratory Science, College of Medical Sciences, Soonchunhyang University, Asan 31538, Republic of Korea.
Jinhye KimCentral Lab., iCONNECTOME Co., Ltd., Cheonan 31168, Republic of Korea.
Sunmi YoonCentral Lab., iCONNECTOME Co., Ltd., Cheonan 31168, Republic of Korea.
Isaac Jinwon YiDepartment of Cognitive Science, University of California, San Diego, CA 92093, USA.
María Inés Morán-ValeroPharmactive Biotech S.L.U., 28049 Madrid, Spain.
Min-Young KwonHyundai Bioland Co., Ltd., Ansan 15407, Republic of Korea.
Johann SohnHyundai Bioland Co., Ltd., Ansan 15407, Republic of Korea.ORCID 0000-0002-4449-9910
Sun-Shin YiBK21 Four Program, Department of Medical Science, Soonchunhyang University, Asan 31538, Republic of Korea.
Soonchunhyang University · KRBioland (South Korea) · KRUniversity of California San Diego · US

Funding

Hyundai Bioland (South Korea) IC22_02Soonchunhyang University
6 · The paper itself

Abstract

Stress-related symptoms are a global concern, impacting millions of individuals, yet effective and safe treatments remain scarce. Although multiple studies have highlighted the stress- alleviating properties of saffron extract, the underlying mechanisms remain unclear. This study employs the unpredictable chronic mild stress (CMS) animal model to investigate the impact of a standardized saffron extract, Affron

Indexed as

CrocusResilience, PsychologicalAnimalsCorticosteroneDepressionHumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemRatsRats, WistarStress, PsychologicalCorticosteroneAffron®depressionhypothalamic–pituitary–adrenal axisneuroplasticitysaffron extractstress hormonesstress resilienceunpredictable chronic mild stress

Identifiers

PMID38068714
PMCPMC10707924
OpenAlexW4388858462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.