Evidence map›Paper›PMID 38068432›Full record

ReviewJournal of clinical medicine2023

Pancreatic Ductal Adenocarcinoma: Update of CT-Based Radiomics Applications in the Pre-Surgical Prediction of the Risk of Post-Operative Fistula, Resectability Status and Prognosis.

Giulia Pacella, Maria Chiara Brunese, Eleonora D'Imperio, Marco Rotondo, Andrea Scacchi, Mattia Carbone, Germano Guerra

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giulia PacellaDepartment of Medicine and Health Science "V. Tiberio", University of Molise, 86100 Campobasso, Italy.
Maria Chiara BruneseDepartment of Medicine and Health Science "V. Tiberio", University of Molise, 86100 Campobasso, Italy.
Eleonora D'ImperioRadiology Unit, "A. Cardarelli" Hospital, 80131 Campobasso, Italy.
Marco RotondoDepartment of Medicine and Health Science "V. Tiberio", University of Molise, 86100 Campobasso, Italy.
Andrea ScacchiGeneral Surgery Unit, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0002-8100-3320
Mattia CarboneSan Giovanni di Dio e Ruggi d'Aragona Hospital, 84131 Salerno, Italy.
Germano GuerraDepartment of Medicine and Health Science "V. Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0002-4342-962X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancreatic ductal adenocarcinoma (PDAC) is the seventh leading cause of cancer-related deaths worldwide. Surgical resection is the main driver to improving survival in resectable tumors, while neoadjuvant treatment based on chemotherapy (and radiotherapy) is the best option-treatment for a non-primally resectable disease. CT-based imaging has a central role in detecting, staging, and managing PDAC. As several authors have proposed radiomics for risk stratification in patients undergoing surgery for PADC, in this narrative review, we have explored the actual fields of interest of radiomics tools in PDAC built on pre-surgical imaging and clinical variables, to obtain more objective and reliable predictors.

methodsThe PubMed database was searched for papers published in the English language no earlier than January 2018.

resultsWe found 301 studies, and 11 satisfied our research criteria. Of those included, four were on resectability status prediction, three on preoperative pancreatic fistula (POPF) prediction, and four on survival prediction. Most of the studies were retrospective.

conclusionsIt is possible to conclude that many performing models have been developed to get predictive information in pre-surgical evaluation. However, all the studies were retrospective, lacking further external validation in prospective and multicentric cohorts. Furthermore, the radiomics models and the expression of results should be standardized and automatized to be applicable in clinical practice.

Indexed as

artificial intelligencepancreatic ductal adenocarcinomaPOPFpresurgical evaluationprognosisradiomic

Identifiers

PMID38068432
PMCPMC10707069

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.